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XB-ART-6953
Biochim Biophys Acta 2002 Jul 19;15763:265-8. doi: 10.1016/s0167-4781(02)00344-5.
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Xwnt-2 (Xwnt-2b) is maternally expressed in Xenopus oocytes and embryos.

Landesman Y , Goodenough DA , Paul DL .


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Xwnt-2 (formerly Xwnt-2b) is a member of the Xwnt-8 class of axis-inducing Wnts. Its zygotic expression is at the prosencephalic-mesencephalic border of the early tadpole brain and above the heart primordium [Mech. Dev. 63 (1997) 199]. Here, we report that Xwnt-2 has an earlier, maternal pattern of expression. It is detected in the oocyte, egg and the developing embryo. Studies of the spatial localization of maternal Xwnt-2 show transcripts in both vegetal and animal blastomeres with enrichment in the animal hemisphere. The identification of maternal Xwnt-2 raises questions about possible roles of dorsalizing Xwnts in axial patterning of the Xenopus embryo.

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Species referenced: Xenopus laevis
Genes referenced: wnt2 wnt2b