XB-ART-8166
Dev Genes Evol
September 1, 2001;
211
(8-9):
442-4.
Identification and expression of zebrafish Iroquois homeobox gene irx1.
Abstract
Iroquois homeoproteins are prepatterning factors that positively regulate proneural genes and control neurogenesis. We have identified a zebrafish Iroquois gene, irx1, which is highly homologous to Xenopus Xiro1, Gallus c-Irx1 and mouse Irx1. Expression of irx1 was initially detected at the bud stage. By 16 h post-fertilization (hpf), irx1 expression was exclusively limited to the prospective midbrain and hindbrain. By 24 hpf, irx1 expression was clearly detected in the acousticovestibual ganglia, tectum, tegmentum, cerebellum and rhombomere 1 but not in rhombomere 2 or mid-hindbrain boundary.
PubMed ID: 11685579
Article link: Dev Genes Evol
Species referenced: Xenopus laevis
Genes referenced: irx1