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Dev Genes Evol September 1, 2001; 211 (8-9): 442-4.

Identification and expression of zebrafish Iroquois homeobox gene irx1.

Cheng CW , Hui C , Strähle U , Cheng SH .

Iroquois homeoproteins are prepatterning factors that positively regulate proneural genes and control neurogenesis. We have identified a zebrafish Iroquois gene, irx1, which is highly homologous to Xenopus Xiro1, Gallus c-Irx1 and mouse Irx1. Expression of irx1 was initially detected at the bud stage. By 16 h post-fertilization (hpf), irx1 expression was exclusively limited to the prospective midbrain and hindbrain. By 24 hpf, irx1 expression was clearly detected in the acousticovestibual ganglia, tectum, tegmentum, cerebellum and rhombomere 1 but not in rhombomere 2 or mid-hindbrain boundary.

PubMed ID: 11685579
Article link: Dev Genes Evol

Species referenced: Xenopus laevis
Genes referenced: irx1