XB-ART-8260Mol Reprod Dev November 1, 2001; 60 (3): 331-7.
In vertebrates, there are six or more copies of genes related to the Drosophila pattern formation homeodomain gene Distal-less. Among this family, Dlx3 and Dlx5 share extensive sequence homology and have similar, but distinctive, expression patterns, suggesting that these two factors may have substantially redundant developmental functions. Here we show that at the earliest phases of embryogenesis in Xenopus, there are significant differences between Dlx3 and Dlx5 expression and that this correlates with different functions in the restriction of neural crest and neural plate boundaries, respectively.
PubMed ID: 11599044
Article link: Mol Reprod Dev
Genes referenced: dlx3 dlx5