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J Mol Evol
2006 Jan 01;621:53-65. doi: 10.1007/s00239-005-0013-7.
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The mariner transposons belonging to the irritans subfamily were maintained in chordate genomes by vertical transmission.
Sinzelle L
,
Chesneau A
,
Bigot Y
,
Mazabraud A
,
Pollet N
.
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Mariner-like elements (MLEs) belong to the Tc1-mariner superfamily of DNA transposons, which is very widespread in animal genomes. We report here the first complete description of a MLE, Xtmar1, within the genome of a poikilotherm vertebrate, the amphibian Xenopus tropicalis. A close relative, XlMLE, is also characterized within the genome of a sibling species, Xenopus laevis. The phylogenetic analysis of the relationships between MLE transposases reveals that Xtmar1 is closely related to Hsmar2 and Bytmar1 and that together they form a second distinct lineage of the irritans subfamily. All members of this lineage are also characterized by the 36- to 43-bp size of their imperfectly conserved inverted terminal repeats and by the -8-bp motif located at their outer extremity. Since XlMLE, Xlmar1, and Hsmar2 are present in species located at both extremities of the vertebrate evolutionary tree, we looked for MLE relatives belonging to the same subfamily in the available sequencing projects using the amino acid consensus sequence of the Hsmar2 transposase as an in silico probe. We found that irritans MLEs are present in chordate genomes including most craniates. This therefore suggests that these elements have been present within chordate genomes for 750 Myr and that the main way they have been maintained in these species has been via vertical transmission. The very small number of stochastic losses observed in the data available suggests that their inactivation during evolution has been very slow.
Auge-Gouillou,
Human and other mammalian genomes contain transposons of the mariner family.
1995, Pubmed
Auge-Gouillou,
Human and other mammalian genomes contain transposons of the mariner family.
1995,
Pubmed
Augé-Gouillou,
The ITR binding domain of the Mariner Mos-1 transposase.
2001,
Pubmed
Barry,
A bacterial genetic screen identifies functional coding sequences of the insect mariner transposable element Famar1 amplified from the genome of the earwig, Forficula auricularia.
2004,
Pubmed
Bauser,
Characterization of hitchhiker, a transposon insertion frequently associated with baculovirus FP mutants derived upon passage in the TN-368 cell line.
1996,
Pubmed
Bigot,
Conservation of Palindromic and Mirror Motifs within Inverted Terminal Repeats of mariner-like Elements.
2005,
Pubmed
Blair Hedges,
Genomic clocks and evolutionary timescales.
2003,
Pubmed
Capy,
The strange phylogenies of transposable elements: are horizontal transfers the only explantation?
1994,
Pubmed
Claudianos,
maT--a clade of transposons intermediate between mariner and Tc1.
2002,
Pubmed
Feschotte,
DNA-binding specificity of rice mariner-like transposases and interactions with Stowaway MITEs.
2005,
Pubmed
Fraser,
Transposon-mediated mutagenesis of a baculovirus.
1985,
Pubmed
Halaimia-Toumi,
The GC-rich transposon Bytmar1 from the deep-sea hydrothermal crab, Bythograea thermydron, may encode three transposase isoforms from a single ORF.
2004,
Pubmed
Kidwell,
Transposable elements and host genome evolution.
2000,
Pubmed
Lampe,
A purified mariner transposase is sufficient to mediate transposition in vitro.
1996,
Pubmed
Lampe,
Recent horizontal transfer of mellifera subfamily mariner transposons into insect lineages representing four different orders shows that selection acts only during horizontal transfer.
2003,
Pubmed
Lander,
Initial sequencing and analysis of the human genome.
2001,
Pubmed
Mandrioli,
Molecular and cytogenetic analysis of the goby Gobius niger (Teleostei, Gobiidae).
2000,
Pubmed
Mandrioli,
Cytogenetic and molecular analysis of the pufferfish Tetraodon fluviatilis (Osteichthyes).
2001,
Pubmed
Medhora,
Molecular and functional analysis of the mariner mutator element Mos1 in Drosophila.
1991,
Pubmed
Nakajima,
A novel tripartite structure comprising a mariner-like element and two additional retrotransposons found in the Bombyx mori genome.
1999,
Pubmed
Petrov,
High intrinsic rate of DNA loss in Drosophila.
1996,
Pubmed
Pietrokovski,
A helix-turn-helix DNA-binding motif predicted for transposases of DNA transposons.
1997,
Pubmed
Robertson,
The mariner transposable element is widespread in insects.
1993,
Pubmed
Robertson,
Bmmar6, a second mori subfamily mariner transposon from the silkworm moth Bombyx mori.
2003,
Pubmed
Robertson,
Molecular evolution of an ancient mariner transposon, Hsmar1, in the human genome.
1997,
Pubmed
Robertson,
Molecular evolution of the second ancient human mariner transposon, Hsmar2, illustrates patterns of neutral evolution in the human genome lineage.
1997,
Pubmed
Roest Crollius,
Characterization and repeat analysis of the compact genome of the freshwater pufferfish Tetraodon nigroviridis.
2000,
Pubmed
Rouleux-Bonnin,
Evolution of full-length and deleted forms of the mariner-like element, Botmar1, in the Genome of the bumble bee, Bombus terrestris (Hymenoptera: Apidae).
2005,
Pubmed
Shao,
Expanding the diversity of the IS630-Tc1-mariner superfamily: discovery of a unique DD37E transposon and reclassification of the DD37D and DD39D transposons.
2001,
Pubmed
Silva,
A potentially functional mariner transposable element in the protist Trichomonas vaginalis.
2005,
Pubmed
Sinzelle,
Characterization of multiple lineages of Tc1-like elements within the genome of the amphibian Xenopus tropicalis.
2005,
Pubmed
,
Xenbase
Southern,
Detection of specific sequences among DNA fragments separated by gel electrophoresis.
1975,
Pubmed
Witherspoon,
Neutral evolution of ten types of mariner transposons in the genomes of Caenorhabditis elegans and Caenorhabditis briggsae.
2003,
Pubmed
Zakharkin,
Identification of two mariner-like elements in the genome of the mosquito Ochlerotatus atropalpus.
2004,
Pubmed
