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XB-ART-9006
Vision Res 2001 Jun 01;4114:1765-70. doi: 10.1016/s0042-6989(01)00053-0.
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Continued neurogenesis is not a pre-requisite for regeneration of a topographic retino-tectal projection.

Beaver RS , Dunlop SA , Harman AM , Stirling RV , Easter SS , Roberts JD , Beazley LD .


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Electrophysiological recording demonstrated that visuo-tectal projections are topographically organised after optic nerve regeneration in aged Xenopus laevis. 3H-thymidine autoradiography confirmed previous reports [Taylor, Lack, & Easter, Eur. Journal of Neuroscience 1 (1989) 626-638] that cell division had already ceased at the retinal ciliary margin. The results demonstrate that, contrary to a previous suggestion [Holder & Clarke, Trends in Neuroscience 11 (1988) 94-99], continued neurogenesis is not a pre-requisite for the re-establishment of appropriate connections with target cells.

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