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Antibody Name: Kif5b Ab1

Common Name: Kinesin 1

RRID: AB_528326
Synonyms: SUK 4

Gene: kif5b

Clone Type: Monoclonal

Clone Number SUK 4
Isotype IgG1
Host Organism mouse
Xenopus Reactivity tropicalis, laevis
Non-Xenopus Reactivity cow, dog, fruitfly, human, mouse, worm
Description: supplied by dshb Cat# SUK 4
Name Kinesin
Type polypeptide
Post Translational Modifications None
Source Organism Other
Description Inhibits sea urchin egg kinesin-induced microtubule translocation. SUK 4 doesn't cross react with squid kinesin. Raised against sea urchin kinesin-1. Head region of kinesin heavy chain containing the microtubule-binding region. The epitope is located on aa 336-390 of the Drosophila kinesin heavy chain which corresponds to aa 328-382 of the urchin protein.
Reported Usage
immunohistochemistry 1:250
western blot
immunoprecipitation Actually immuno-inhibition/suppression
First: Inhibition of kinesin-driven microtubule motility by monoclonal antibodies to kinesin heavy chains., J Cell Biol 1988  
Most recent: Kinesin-1 heavy chain mediates microtubule sliding to drive changes in cell shape., Proc Natl Acad Sci U S A 2010  
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