Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
Summary Images Attributions Wiki Source
XB-ANTIBODY-14579487

Antibody Name: Kif5b Ab1

Common Name: Kinesin 1

RRID: AB_528326
Synonyms: SUK 4

Antigens
Gene: kif5b

Clone Type: Monoclonal
Source:

Antibody
Clone Number SUK 4
Purification
Isotype IgG1
Host Organism mouse
Xenopus Reactivity tropicalis, laevis
Non-Xenopus Reactivity cow, dog, fruitfly, human, mouse, worm
Description: supplied by dshb Cat# SUK 4
Immunogen
Name Kinesin
Type polypeptide
Post Translational Modifications None
Source Organism Other
Description Inhibits sea urchin egg kinesin-induced microtubule translocation. SUK 4 doesn't cross react with squid kinesin. Raised against sea urchin kinesin-1. Head region of kinesin heavy chain containing the microtubule-binding region. The epitope is located on aa 336-390 of the Drosophila kinesin heavy chain which corresponds to aa 328-382 of the urchin protein.
Sequence
Reported Usage
immunohistochemistry 1:250
western blot
immunoprecipitation Actually immuno-inhibition/suppression
immunofluorescence
Publications
First: Inhibition of kinesin-driven microtubule motility by monoclonal antibodies to kinesin heavy chains., J Cell Biol 1988  
Most recent: Kinesin-1 heavy chain mediates microtubule sliding to drive changes in cell shape., Proc Natl Acad Sci U S A 2010  
View All Papers