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XB-ANTIBODY-14579487
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Antibody Name:
Kif5b Ab1
Common Name: Kinesin 1 RRID: AB_528326 Synonyms: kinesin heavy chain, head region, SUK 4
Source: |
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| Antibody | |
| Clone Number | SUK 4 |
| Purification | |
| Isotype | IgG1 |
| Host Organism | mouse |
| Xenopus Reactivity | |
| Non-Xenopus Reactivity | |
| Description: | Inhibits sea urchin egg kinesin-induced microtubule translocation. Head region of kinesin heavy chain containing the microtubule-binding region.. SUK 4 doesn't cross react with squid kinesin. In mice, SUK 4 recognizes the three kinesin-1 KIF5A, KIF5B and KIF5C, with a more intense stainning for KIF5A Citation:(DSHB Cat# SUK 4, RRID:AB_528326). and PMID:2974459 |
| Immunogen | |
| Name | Kinesin 1 |
| Type | polypeptide |
| Post Translational Modifications | None |
| Source Organism | Other |
| Description | Raised against Full length protein of sea urchin kinesin-1. The epitope is located on aa 336-390 of the Drosophila kinesin heavy chain which corresponds to aa 328-382 of the urchin protein. |
| Sequence | |
| Reported Usage | |
| immunohistochemistry | 1:250 |
| immunoprecipitation | Actually immuno-inhibition/suppression |
| immunofluorescence | |
| western blot | |
| Used For Epitope Tagging | Yes |
| Publications | |
| ???displayAntibody.papersFirst??? |
Inhibition of kinesin-driven microtubule motility by monoclonal antibodies to kinesin heavy chains., J Cell Biol 1988 |
| ???displayAntibody.papersRecent??? |
Kinesin-1 heavy chain mediates microtubule sliding to drive changes in cell shape., Proc Natl Acad Sci U S A 2010 |
| ???displayAntibody.papersAll??? | |
