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XB-ANTIBODY-14579746

Antibody Name: Polr2a Ab1

Common Name:

RRID:
Synonyms:

Antigens
Gene: polr2a

Clone Type: Monoclonal
Source: Eurogentec/Covance

Antibody
Clone Number H5
Purification Ascites
Isotype IgM
Host Organism mouse
Xenopus Reactivity tropicalis
Non-Xenopus Reactivity
Description: Supplied by Covance, cat# MMS-129R The antibody H5 was developed against a purified phosphorylated form of RNA polymerase II extracted from a transformed cell line. Pol II has two physiologically important phosphorylation sites; ser-2 and ser-5. Both sites are found in the heptapeptide repeat YSPTSPS at the C-terminal domain. This antibody recognizes the phosphoserine 2 version of pol II.
Immunogen
Name RNA Pol II (S2)
Type polypeptide
Post Translational Modifications Phosphorylated
Source Organism Other
Description
Sequence
Reported Usage
immunohistochemistry Dilution 1:50, 1:100
Publications
First: Nuclear actin polymerization is required for transcriptional reprogramming of Oct4 by oocytes., Genes Dev 2011      
Most recent: Xenopus Nanos1 is required to prevent endoderm gene expression and apoptosis in primordial germ cells., Development 2012                  
View All Papers

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