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XB-ANTIBODY-14994433

Antibody Name: Smad1 Ab8

Common Name: phospho-Smad1/5

RRID:
Synonyms: 41D10, 9516, P-Smad1/5

Antigens
Gene: smad1

Clone Type: Monoclonal
Source: Cell Signaling Technology

Antibody
Clone Number 41D10
Purification
Isotype IgG
Host Organism rabbit
Xenopus Reactivity tropicalis, laevis
Non-Xenopus Reactivity
Description: Supplied by Cell Signaling Technology: #9516. Phospho-Smad1/5 (Ser463/465) (41D10) Rabbit mAb detects endogenous levels of Smad1/5 only when dually phosphorylated at Ser463 and Ser465. The antibody does not cross-react with other Smad-related proteins.
Immunogen
Name phospho-smad1
Type synthetic sequence
Post Translational Modifications Phosphorylated
Source Organism human
Description Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser463/465 of human Smad5.
Sequence
Reported Usage
western blot Dilution of 1:200
Publications
First: Smurf1 regulates neural patterning and folding in Xenopus embryos by antagonizing the BMP/Smad1 pathway., Dev Biol 2006                        
Most recent: Tril targets Smad7 for degradation to allow hematopoietic specification in Xenopus embryos., Development 2016                              
View All Papers

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