|
XB-ANTIBODY-17311775
Antibody Name:
Aurka Ab5
Common Name: Aurora A RRID: Synonyms: Eg2, sc-27884
Source: |
|
Antibody | |
Clone Number | xG-14 |
Purification | |
Isotype | IgG |
Host Organism | goat |
Xenopus Reactivity | X. tropicalis, X. laevis |
Non-Xenopus Reactivity | |
Description: | Santa Cruz Biotechnology |
Immunogen | |
Name | aurka |
Type | polypeptide |
Post Translational Modifications | None |
Source Organism | frog |
Description | Activation of the oncogenic protein kinase Aurora A regulates meiotic and mitotic cell cycles in eukaryotic cells. Specifically, Aurora A plays a key role in G2/M progression. Activation occurs via autophosphorylation, and while 14 sites are subject to this, only the threonine residue at position 295 is required for activity. Though autophosphorylation mediates activation, a number of other proteins influence activation, including the spindle assembly factor TPX2 and p53. |
Sequence | |
Reported Usage | |
Publications | |
???displayAntibody.papersFirst??? |
Xenopus laevis as a Model to Identify Translation Impairment., J Vis Exp 2015 |
???displayAntibody.papersRecent??? | |
???displayAntibody.papersAll??? |