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XB-ANTIBODY-22250333

Antibody Name: Pak1 Pak2 Pak3 Ab3

Common Name: phospho-Pak (T423)

RRID: AB_303091
Synonyms: PAK1 + PAK2 + PAK3 (phospho T423) antibody, ab2477, phospho-Pak (T423) , total Pak1,2,3

Antigens
Gene: pak3 , pak2 , pak1

Clone Type: Polyclonal
Source: Abcam

Antibody
Clone Number
Purification Affinity Purification
Isotype IgG
Host Organism rabbit
Xenopus Reactivity laevis
Non-Xenopus Reactivity human
Description: This phospho specific polyclonal antibody is specific for phosphorylated Threonine 423 of Human PAK 1 + 2 + 3. Reactivity with non-phosphorylated PAK 1 + 2 + 3 is less than 1% by ELISA. Cite this (Abcam Cat# ab2477, RRID:AB_303091)
Immunogen
Name Pak1,2,3
Type synthetic sequence
Post Translational Modifications Phosphorylated
Source Organism human
Description Synthetic peptide: EQSKRSTpMVGTPY conjugated to KLH, corresponding to amino acids 413-433 of Human PAK 1, 408-428 of human PAK 2 and 411-431 of human PAK 3.
Sequence
Reported Usage
western blot 1:500 - 1:2000. Detects a band of approximately 65 kDa.
Publications
First: GSK3 Inhibits Macropinocytosis and Lysosomal Activity through the Wnt Destruction Complex Machinery., Cell Rep 2020                                        
Most recent:
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