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XB-ANTIBODY-14574776

Antibody Name: Cdh3 Ab1

Common Name: C-cadherin

RRID: AB_528113
Synonyms: 6b6, C-cadherin, C_cadherin, c cadherin

Antigens
Gene: cdh3
GO: plasma membrane

Clone Type: Monoclonal
Source:

Antibody
Clone Number 6B6
Purification obsolete soluble fraction
Isotype IgG1
Host Organism mouse
Xenopus Reactivity tropicalis, laevis
Non-Xenopus Reactivity
Description: Generated by Barry Gumbiner. Available at Developmental Studies Hybridoma Bank (DSHB) clone# 6B6. Citation: (DSHB Cat# 6b6, RRID:AB_528113). Please email citation to DSHB. Can be used to block cdh3 function/cell adhesion
Immunogen
Name CEC1-5
Type polypeptide
Post Translational Modifications None
Source Organism frog
Description This antibody blocks aggregation of embryonic blastomeres. Fusion protein containing a portion of glutathione-S transferase fused to the amino terminus of a large portion of the C-cadherin extracellular domain (containing about two thirds of domain EC2 and the region from EC2 to just before the transmembrane domain).
Sequence
Reported Usage
western blot
immunoprecipitation
immunofluorescence with TCA fixation
Publications
First: Regulation of C-cadherin function during activin induced morphogenesis of Xenopus animal caps., J Cell Biol 1994  
Most recent: Mechanical Stress Regulates Epithelial Tissue Integrity and Stiffness through the FGFR/Erk2 Signaling Pathway during Embryogenesis., Cell Rep 2020                  
View All Papers

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