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XB-ANTIBODY-14578968

Antibody Name: Casp3 Ab1

Common Name: Cleaved caspase-3 (Asp175)

RRID:
Synonyms: 9661, Asp175, Asp175, active caspase 3

Antigens
Gene: casp3

Clone Type: Polyclonal
Source: Cell Signaling Technology

Antibody
Clone Number #9661
Purification Affinity Purification
Isotype isotype unknown
Host Organism rabbit
Xenopus Reactivity Tropicalis, Laevis
Non-Xenopus Reactivity human, monkey, mouse, rat
Description: Supplied by Cell Signaling Technology cat #9661L & 9661S
Immunogen
Name Cleaved caspase
Type polypeptide
Post Translational Modifications Proteolysis
Source Organism human
Description Cleaved Caspase-3 (Asp175) Antibody detects endogenous levels of the large fragment (17/19 kDa) of activated caspase-3 resulting from cleavage adjacent to Asp175. This antibody does not recognize full length caspase-3 or other cleaved caspases. This antibody detects non-specific caspase substrates by western blot.
Sequence
Reported Usage
immunofluorescence 1:300
immunohistochemistry
western blot
Publications
First: Barhl2 limits growth of the diencephalic primordium through Caspase3 inhibition of beta-catenin activation. [Proc Natl Acad Sci U S A 2011]
Most recent: Neuronal degeneration and regeneration induced by axotomy in the olfactory epithelium of Xenopus laevis. [Dev Neurobiol 2017]
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