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Antibody Name: Casp3 Ab1 Common Name: Cleaved caspase-3 (Asp175) RRID: AB_2341188 Synonyms: 9661, 9661S, Asp175, active caspase 3 Antigens Gene: casp3.2 Clone Type: Polyclonal Source: Cell Signaling Technology

Antibody
Clone Number	#9661
Purification	Affinity Purification
Isotype	isotype unknown
Host Organism	rabbit
Xenopus Reactivity	X. tropicalis, X. laevis
Non-Xenopus Reactivity	human, monkey, mouse, rat
Description:	Supplied by Cell Signaling Technology cat #9661L & 9661S. CITE this: (Cell Signaling Technology Cat# 9661, RRID:AB_2341188)
Immunogen
Name	Cleaved caspase
Type	polypeptide
Post Translational Modifications	Proteolysis
Source Organism	human
Description	Cleaved Caspase-3 (Asp175) Antibody detects endogenous levels of the large fragment (17/19 kDa) of activated caspase-3 resulting from cleavage adjacent to Asp175. This antibody does not recognize full length caspase-3 or other cleaved caspases. This antibody detects non-specific caspase substrates by western blot.
Sequence
Reported Usage
immunohistochemistry
western blot	1:500 dilution
immunofluorescence	1:300
Publications
???displayAntibody.papersFirst???	Barhl2 limits growth of the diencephalic primordium through Caspase3 inhibition of beta-catenin activation., Proc Natl Acad Sci U S A 2011
???displayAntibody.papersRecent???	TBC1D32 variants disrupt retinal ciliogenesis and cause retinitis pigmentosa., JCI Insight 2023
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