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XB-ANTIBODY-14578968

Antibody Name: Casp3 Ab1

Common Name: Cleaved caspase-3 (Asp175)

RRID: AB_2341188
Synonyms: 9661, 9661S, 9661S, Asp175, Asp175, active caspase 3

Antigens
Gene: casp3.2

Clone Type: Polyclonal
Source: Cell Signaling Technology

Antibody
Clone Number #9661
Purification Affinity Purification
Isotype isotype unknown
Host Organism rabbit
Xenopus Reactivity tropicalis, laevis
Non-Xenopus Reactivity human, monkey, mouse, rat
Description: Supplied by Cell Signaling Technology cat #9661L & 9661S. CITE this: (Cell Signaling Technology Cat# 9661, RRID:AB_2341188)
Immunogen
Name Cleaved caspase
Type polypeptide
Post Translational Modifications Proteolysis
Source Organism human
Description Cleaved Caspase-3 (Asp175) Antibody detects endogenous levels of the large fragment (17/19 kDa) of activated caspase-3 resulting from cleavage adjacent to Asp175. This antibody does not recognize full length caspase-3 or other cleaved caspases. This antibody detects non-specific caspase substrates by western blot.
Sequence
Reported Usage
immunohistochemistry
western blot 1:500 dilution
immunofluorescence 1:300
Publications
First: Barhl2 limits growth of the diencephalic primordium through Caspase3 inhibition of beta-catenin activation., Proc Natl Acad Sci U S A 2011                      
Most recent: The neurodevelopmental disorder risk gene DYRK1A is required for ciliogenesis and control of brain size in Xenopus embryos., Development 2020                              
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