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XB-ANTIBODY-14579093

Antibody Name: Col2a1 Ab2

Common Name: Collagen type II

RRID: AB_528164
Synonyms: CIIC1

Antigens
Gene: col2a1
XAO: cartilage tissue, extracellular matrix

Clone Type: Monoclonal
Source:

Antibody
Clone Number CIIC1
Purification
Isotype IgG2a
Host Organism mouse
Xenopus Reactivity tropicalis, laevis
Non-Xenopus Reactivity chicken, cow, human, mouse, pig, rabbit, rat
Description: Citation: (DSHB Cat# ciic1, RRID:AB_528164). Please email citation to DSHB.
Immunogen
Name collagen type II
Type polypeptide
Post Translational Modifications None
Source Organism chicken
Description cartilage Stains hyaluronidase-treated fetal and adult mouse and human cartilage in vitro as well as mouse cartilage in vivo. This antibody recognizes native triple-helical type II collagen. It does not bind to denatured type II collagen (PMID: 25005029). he CIIC1 antibody induces sub clinical arthritis if injected at low (0.5 mg) doses and clinical arthritis in mice if injected at higher doses and in combination with other antibodies (see [PMID: 16125192]).
Sequence [+]
Reported Usage
immunohistochemistry
western blot
immunofluorescence
enzyme-linked immunosorbent assay
Publications
First: Characterization of the antibody response in mice with type II collagen-induced arthritis, using monoclonal anti-type II collagen antibodies., Arthritis Rheum 1986  
Most recent:
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