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XB-ANTIBODY-14579213
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Antibody Name:
Tpm1 Ab1
Common Name: tropomyosin RRID: AB_2205770 Synonyms: CH1, Tmy
Source: Developmental Studies Hybridoma Bank |
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| Antibody | |
| Clone Number | CH1 |
| Purification | |
| Isotype | IgG1 |
| Host Organism | mouse |
| Xenopus Reactivity | tropicalis, laevis |
| Non-Xenopus Reactivity | chicken, human, mouse, rat, zebrafish |
| Description: | Supplied by DSHB, Cat# CH1. Citation: (DSHB Cat# CH1, RRID:AB_2205770). Please email citation to DSHB. |
| Immunogen | |
| Name | muscle tropomyosin |
| Type | polypeptide |
| Post Translational Modifications | None |
| Source Organism | chicken |
| Description | chicken muscle tropomyosin CH1 reacts strongly with striated muscle forms of tropomyosin, including cardiac alpha-tropomyosin and skeletal alpha- and beta-tropomyosins, but not with tropomyosin isoforms from gizzard (smooth muscle) or chicken embryo fibroblasts. CH1 interferes with the binding of tropomyosin to actin. CH1 recognizes sarcomeric Tm soforms alpha-fast, beta, and alpha-slow with poor affinity for alpha-slow. |
| Sequence |
[+]
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| Reported Usage | |
| western blot | |
| immunoprecipitation | |
| immunofluorescence | Fix with Dents or PFA |
| enzyme-linked immunosorbent assay | |
| Publications | |
| First: |
Monoclonal antibodies against chicken tropomyosin isoforms: production, characterization, and application., Hybridoma 1985 |
| Most recent: |
Spatiotemporally Controlled Mechanical Cues Drive Progenitor Mesenchymal-to-Epithelial Transition Enabling Proper Heart Formation and Function., Curr Biol 2017  |
| View All Papers | |
