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XB-ANTIBODY-14579213
Antibody Name:
Tpm1 Ab1
Common Name: tropomyosin RRID: AB_2205770 Synonyms: CH1, Tmy
Source: Developmental Studies Hybridoma Bank |
Antibody | |
Clone Number | CH1 |
Purification | |
Isotype | IgG1 |
Host Organism | mouse |
Xenopus Reactivity | tropicalis, laevis |
Non-Xenopus Reactivity | chicken, human, mouse, rat, zebrafish |
Description: | Supplied by DSHB, Cat# CH1. Citation: (DSHB Cat# CH1, RRID:AB_2205770). Please email citation to DSHB. |
Immunogen | |
Name | muscle tropomyosin |
Type | polypeptide |
Post Translational Modifications | None |
Source Organism | chicken |
Description | chicken muscle tropomyosin CH1 reacts strongly with striated muscle forms of tropomyosin, including cardiac alpha-tropomyosin and skeletal alpha- and beta-tropomyosins, but not with tropomyosin isoforms from gizzard (smooth muscle) or chicken embryo fibroblasts. CH1 interferes with the binding of tropomyosin to actin. CH1 recognizes sarcomeric Tm soforms alpha-fast, beta, and alpha-slow with poor affinity for alpha-slow. |
Sequence |
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Reported Usage | |
western blot | |
immunoprecipitation | |
immunofluorescence | Fix with Dents or PFA |
enzyme-linked immunosorbent assay | |
Publications | |
First: |
Monoclonal antibodies against chicken tropomyosin isoforms: production, characterization, and application., Hybridoma 1985 |
Most recent: |
Spatiotemporally Controlled Mechanical Cues Drive Progenitor Mesenchymal-to-Epithelial Transition Enabling Proper Heart Formation and Function., Curr Biol 2017 ![]() |
View All Papers |