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XB-ANTIBODY-14579519

Antibody Name: Polr2a Ab4

Common Name: phospho-RNA Pol II

RRID:
Synonyms: H14, MMS-134R

Antigens
Gene: polr2a

Clone Type: Monoclonal
Source:

Antibody
Clone Number H14
Purification Ascites
Isotype IgM
Host Organism mouse
Xenopus Reactivity tropicalis
Non-Xenopus Reactivity
Description: Supplied by Covance, cat# MMS-134R
Immunogen
Name RNA pol II
Type polypeptide
Post Translational Modifications Phosphorylated
Source Organism frog
Description The antibody H14 was developed against a purified phosphorylated form of RNA polymerase II extracted from a transformed cell line. Pol II has two physiologically important phosphorylation sites; ser-2 and ser-5. Both sites are found in the heptapeptide repeat YSPTSPS at the C-terminal domain. This antibody recognizes the phosphoserine 5 version of pol II.
Sequence
Reported Usage
immunohistochemistry Dilution 1:100
Publications
First: Repression of zygotic gene expression in the Xenopus germline., Development 2010        
Most recent:
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