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Summary Images Attributions Wiki Source
XB-ANTIBODY-14586377

Antibody Name: Ptk2 Ab1

Common Name: fak

RRID:
Synonyms: 44-624G, 44624G

Antigens
Gene: ptk2
XAO: neuron, spinal nerve

Clone Type: Polyclonal
Source: Thermo Fisher

Antibody
Clone Number
Purification
Isotype IgG
Host Organism rabbit
Xenopus Reactivity tropicalis, laevis
Non-Xenopus Reactivity chicken, fruitfly, human, mouse
Description: supplied by life technologies, formerly biosource international, cat# is reckoned to be 44-624G
Immunogen
Name phospho-Ptk2
Type polypeptide
Post Translational Modifications Phosphorylated
Source Organism frog
Description his purified Rabbit FAK [pY397] polyclonal antibody recognizes FAK that is phosphorylated at tyrosine 397. Focal Adhesion Kinase plays a central role in cell spreading, differentiation, migration, cell death and acceleration of the G1 to S phase of the cell cycle. Rabbit FAK [pY397] polyclonal antibody has been validated for use in western blot applications. Previous lots of FAK [pY397] polyclonal antibody have been validated for use in immunocytochemistry and immunohistochemistry.
Sequence
Reported Usage
immunohistochemistry
western blot 125 kDa band
immunofluorescence 1:300
Publications
First: Local calcium transients contribute to disappearance of pFAK, focal complex removal and deadhesion of neuronal growth cones and fibroblasts., Dev Biol 2005                  
Most recent: Calpain-Mediated Proteolysis of Talin and FAK Regulates Adhesion Dynamics Necessary for Axon Guidance., J Neurosci 2017                  
View All Papers