Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
Summary Images Attributions Wiki Source
XB-ANTIBODY-17252116

Antibody Name: Lrp6 Ab1

Common Name: anti-Phospho-LRP6

RRID:
Synonyms: 2568

Antigens
Gene: lrp6

Clone Type: Polyclonal
Source: Cell Signaling Technology

Antibody
Clone Number
Purification Affinity Purification
Isotype isotype unknown
Host Organism rabbit
Xenopus Reactivity tropicalis, laevis
Non-Xenopus Reactivity human, mouse
Description: Supplied by Cell technology CAT#2568.
Immunogen
Name lrp6
Type synthetic sequence
Post Translational Modifications Phosphorylated
Source Organism frog
Description Phospho-LRP6 (Ser1490) Antibody detects endogenous levels of LRP6 protein when phosphorylated at serine 1490. It is expected, although not yet confirmed, to also detect endogenous levels of LRP5 protein when phosphorylated at serine 1493 (corresponding to serine 1490 in LRP6). Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser1490 of human LRP6.
Sequence
Reported Usage
western blot 1:1000 dilution
Publications
First: Notum is required for neural and head induction via Wnt deacylation, oxidation, and inactivation., Dev Cell 2015                                    
Most recent: Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover., Dev Cell 2017                                  
View All Papers