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XB-ANTIBODY-17328315

Antibody Name: Mbp Ab2

Common Name: ab92406

RRID:
Synonyms: xmbp.1

Antigens
XAO: central nervous system, nerve, myelin accumulating cell

Clone Type: Monoclonal
Source:

Antibody
Clone Number 12
Purification
Isotype IgG
Host Organism rat
Xenopus Reactivity tropicalis, laevis
Non-Xenopus Reactivity cow, human, mouse, pig, rabbit, rat
Description: The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. Abcam
Immunogen
Name myelin basic protein
Type synthetic sequence
Post Translational Modifications unknown post translational modifications
Source Organism frog
Description ab92406 reacts weakly with peptides ending in the Phe 91 where the 91-92 Phe-Phe bond is broken. Synthetic peptide 82-99 reacts very well, as does intact MBP. Further epitope analysis indicates binding to a region defined by amino acids 82-87.
Sequence
Reported Usage
immunohistochemistry
Publications
First: Astrocytes phagocytose focal dystrophies from shortening myelin segments in the optic nerve of Xenopus laevis at metamorphosis., Proc Natl Acad Sci U S A 2015                                            
Most recent:
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