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XB-ANTIBODY-18328516
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Antibody Name:
HIST1H2AA Ab1
Common Name: H2AK119ub RRID: AB_10891618 Synonyms: 8240, Rabbit anti H2AK119ub, Ubiquityl-Histone H2A (Lys119), anti-H2AA
Source: Cell Signaling Technology |
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| Antibody | |
| Clone Number | D27C4 |
| Purification | |
| Isotype | IgG |
| Host Organism | rabbit |
| Xenopus Reactivity | X. laevis |
| Non-Xenopus Reactivity | fruitfly, human, monkey, rat |
| Description: | Ubiquityl-Histone H2A (Lys119) (D27C4) XPA Rabbit mAb recognizes endogenous levels of histone H2A protein only when ubiquitinated at Lys119. The antibody does not cross-react with other ubiquitinated proteins or free ubiquitin. |
| Immunogen | |
| Name | H2AK119ub |
| Type | synthetic sequence |
| Post Translational Modifications | Ubiquitination |
| Source Organism | rabbit |
| Description | Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human histone H2A protein in which Lys119 is mono-ubiquitinated. |
| Sequence | |
| Reported Usage | |
| chromatin immunoprecipitation | 1ul, undiluted |
| Publications | |
| ???displayAntibody.papersFirst??? |
Gene Resistance to Transcriptional Reprogramming following Nuclear Transfer Is Directly Mediated by Multiple Chromatin-Repressive Pathways., Mol Cell 2017  |
| ???displayAntibody.papersRecent??? |
Recognition of H2AK119ub plays an important role in RSF1-regulated early Xenopus development., Front Cell Dev Biol 2023  |
| ???displayAntibody.papersAll??? | |
