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XB-ANTIBODY-18396199

Antibody Name: H2afx Ab2

Common Name: Anti-phospho-Histone H2A.X

RRID: AB_309864
Synonyms: 05-636, H2AXS139P, Histone H2A.X (phospho S139), JBW301

Antigens
Gene: h2axl , h2ax.2

Clone Type: Monoclonal
Source: EMD Millipore

Antibody
Clone Number JBW301
Purification Affinity Purification
Isotype IgG1
Host Organism mouse
Xenopus Reactivity tropicalis, laevis
Non-Xenopus Reactivity human
Description: Anti-phospho-Histone H2A.X (Ser139), clone JBW301 is a well published Mouse Monoclonal Antibody validated in ChIP, ICC, IF, WB. This purified mAb is highly specific for phospho-Histone H2AFX (Ser139).
Immunogen
Name H2AFX
Type polypeptide
Post Translational Modifications Phosphorylated
Source Organism human
Description peptide (C-KATQA[pS]QEY) corresponding to amino acids 134-142 of human histone H2AFX.
Sequence
Reported Usage
immunohistochemistry
Publications
First: Sexually dimorphic expression of Dmrt1 and γH2AX in germ stem cells during gonadal development in Xenopus laevis., FEBS Open Bio 2016                
Most recent: Paternal chromosome loss and metabolic crisis contribute to hybrid inviability in Xenopus., Nature 2018        
View All Papers

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