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XB-MORPHOLINO-17249271
Attributions for cdknx MO1
Papers
Ascl1 phospho-status regulates neuronal differentiation in a Xenopus developmental model of neuroblastoma.
, Wylie LA, Hardwick LJ, Papkovskaia TD, Thiele CJ,
Philpott A
.,
Dis Model Mech. May 1, 2015; 8 (5): 429-41.
The phosphorylation status of
Ascl1 is a key determinant of neuronal differentiation and maturation in vivo and in vitro.
, Ali FR, Cheng K, Kirwan P, Metcalfe S, Livesey FJ, Barker RA, Philpott A.,
Development. June 1, 2014; 141 (11): 2216-24.
Cell cycle-regulated multi-site phosphorylation of
Neurogenin 2 coordinates cell cycling with differentiation during neurogenesis.
, Ali F, Hindley C, McDowell G, Deibler R, Jones A, Kirschner M, Guillemot F, Philpott A.,
Development. October 1, 2011; 138 (19): 4267-77.
Normal levels of
p27 are necessary for
somite segmentation and determining pronephric organ size.
, Naylor RW, Collins RJ,
Philpott A
,
Jones EA
.,
Organogenesis. October 1, 2009; 5 (4): 201-10.
Xhairy2 functions in Xenopus
lens development by regulating
p27(
xic1) expression.
, Murato Y, Hashimoto C.,
Dev Dyn. September 1, 2009; 238 (9): 2179-92.
Cardiac differentiation in Xenopus requires the cyclin-dependent kinase inhibitor,
p27Xic1.
, Movassagh M,
Philpott A
.,
Cardiovasc Res. August 1, 2008; 79 (3): 436-47.
Notch targets the Cdk inhibitor
Xic1 to regulate differentiation but not the cell cycle in neurons.
, Vernon AE, Movassagh M, Horan I, Wise H, Ohnuma S, Philpott A.,
EMBO Rep. June 1, 2006; 7 (6): 643-8.
The cdk inhibitor
p27Xic1 is required for differentiation of primary neurones in Xenopus.
, Vernon AE, Devine C, Philpott A.,
Development. January 1, 2003; 130 (1): 85-92.
A single cdk inhibitor,
p27Xic1, functions beyond cell cycle regulation to promote
muscle differentiation in Xenopus.
, Vernon AE,
Philpott A
.,
Development. January 1, 2003; 130 (1): 71-83.