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Summary Attributions Wiki
XB-MORPHOLINO-18328632
Morpholino Name: tril MO1
Synonyms:
Target mRNA: tril

Morpholino Type: uncategorized morpholino
Sequence: 5' CCAAAATCTGGGCATCACCTTTC 3'

Source: Gene Tools LLC


Target mRNA tropicalis laevis.L laevis.S
Identities 23/23 23/23 23/23
genome
MO
 
5' GAAAGGTGATGCCCAGATTTTGG 3'
   |||||||||||||||||||||||
3' CTTTCCACTACGGGTCTAAAACC 5'
 
5' GAAAGGTGATGCCCAGATTTTGG 3'
   |||||||||||||||||||||||
3' CTTTCCACTACGGGTCTAAAACC 5'
 
5' GAAAGGTGATGCCCAGATTTTGG 3'
   |||||||||||||||||||||||
3' CTTTCCACTACGGGTCTAAAACC 5'
    
Genomic Alignments Position Identity Strand Target Target mRNA
laevis 10.1 Chr6L:44467782..44467804 23/23 Antisense target tril.L
Chr6S:35748068..35748090 23/23 Antisense target tril.S
Chr2S:23138583..23138605 19/23 Antisense off-target LOC108709253
Chr6L:88862989..88863011 20/23 unknown
Chr2L:171474872..171474894 19/23 unknown
Chr8S:51466740..51466762 19/23 unknown
tropicalis 10.0 Chr6:43196607..43196629 23/23 Antisense target tril
Chr4:96519075..96519097 20/23 Antisense off-target rab3b
Chr4:13244737..13244759 19/23 Antisense off-target chrm4
Chr4:13245255..13245277 19/23 Antisense off-target chrm4
Chr8:115793029..115793051 19/23 Antisense off-target pacs2
Chr4:79366868..79366890 20/23 unknown
Publications
???morpholino.displaySummary.papersFirst??? Tril targets Smad7 for degradation to allow hematopoietic specification in Xenopus embryos., Development 2016                              
???morpholino.displaySummary.papersRecent??? Tril dampens Nodal signaling through Pellino2- and Traf6-mediated activation of Nedd4l., Proc Natl Acad Sci U S A 2021                        
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