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Summary Attributions Wiki
XB-MORPHOLINO-18375514
Morpholino Name: pfkfb4 MO2
Synonyms:
Target mRNA: pfkfb4

Morpholino Type: splice blocking morpholino
Sequence: 5' TCCATCCCACAAGCCATTACCTTTC 3'

Source: Gene Tools LLC


Target mRNA tropicalis laevis.L laevis.S
Identities 25/25 21/25 22/25
genome
MO
 
5' GAAAGGTAATGGCTTGTGGGATGGA 3'
   |||||||||||||||||||||||||
3' CTTTCCATTACCGAACACCCTACCT 5'
 
5' GAAAGGTAATGACTTGAGGGATGCG 3'
   ||||||||||| |||| ||||||  
3' CTTTCCATTACCGAACACCCTACCT 5'
 
5' GAAAGGTAATGGTTTGCGGGATGCA 3'
   |||||||||||| ||| |||||| |
3' CTTTCCATTACCGAACACCCTACCT 5'
    
Genomic Alignments Position Identity Strand Target Target mRNA
laevis 10.1 Chr4S:103062031..103062055 22/25 Antisense target pfkfb4.S
Chr4L:122132087..122132111 21/25 Antisense target pfkfb4.L
Chr1L:213399472..213399496 21/25 Antisense off-target ttc33.L
Chr2L:161846555..161846579 21/25 Sense off-target stard13.L
Chr5L:149528365..149528389 21/25 Sense off-target atp6v1c2.L
Chr2L:163473900..163473924 22/25 unknown
tropicalis 10.0 Chr4:123798135..123798159 25/25 Antisense target pfkfb4
Chr5:32210073..32210097 21/25 unknown
Chr6:131625861..131625885 21/25 unknown
Publications
???morpholino.displaySummary.papersFirst??? PFKFB4 controls embryonic patterning via Akt signalling independently of glycolysis., Nat Commun 2015  
???morpholino.displaySummary.papersRecent??? PFKFB4 control of AKT signaling is essential for premigratory and migratory neural crest formation., Development 2017                                  
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