|
XB-MORPHOLINO-22249065
Morpholino Name:
fbrsl1 MO1
Synonyms: fbrsl1 E1/I1
Target mRNA: fbrsl1
Morpholino Type: splice blocking morpholino (E1-I1)
Sequence: 5' ATAACTCTCTCTTACCTCTAAGGCT 3'
Source: Gene Tools LLC
Synonyms: fbrsl1 E1/I1
Target mRNA: fbrsl1
Morpholino Type: splice blocking morpholino (E1-I1)
Sequence: 5' ATAACTCTCTCTTACCTCTAAGGCT 3'
Source: Gene Tools LLC
| Target mRNA | tropicalis | laevis.L | laevis.S | ||||
| Identities | 24/25 | 25/25 | 24/25 | ||||
genome
MO
|
5' AGCCTTAGAGGTAAGAAAGAGTTAT 3'
|||||||||||||||| ||||||||
3' TCGGAATCTCCATTCTCTCTCAATA 5' |
5' AGCCTTAGAGGTAAGAGAGAGTTAT 3' ||||||||||||||||||||||||| 3' TCGGAATCTCCATTCTCTCTCAATA 5' |
5' AGCCTTAGAGGTAAGAAAGAGTTAT 3'
|||||||||||||||| ||||||||
3' TCGGAATCTCCATTCTCTCTCAATA 5' |
||||
Genomic Alignments  |
Position | Identity | Strand | Target | Target mRNA | ||
| laevis 10.1 | Chr1L:169236978..169237002 | 25/25 | Sense | target | fbrsl1.L | ||
| Chr1S:144612882..144612906 | 24/25 | Sense | target | fbrsl1.S | |||
| Chr8L:51239730..51239754 | 21/25 | Antisense | off-target | KIAA1210.L | |||
| Chr1S:119764056..119764080 | 21/25 | Sense | off-target | LOC121399438 | |||
| Chr1S:116486625..116486649 | 21/25 | Antisense | unknown | ||||
| Chr1S:116606854..116606878 | 21/25 | Antisense | unknown | ||||
| Chr1S:116650759..116650783 | 21/25 | Antisense | unknown | ||||
| Chr1S:116730629..116730653 | 21/25 | Antisense | unknown | ||||
| Chr1S:116832198..116832222 | 21/25 | Antisense | unknown | ||||
| Chr1S:116879346..116879370 | 21/25 | Antisense | unknown | ||||
| Chr1S:117249168..117249192 | 21/25 | Sense | unknown | ||||
| Chr1S:117286066..117286090 | 21/25 | Sense | unknown | ||||
| Chr1S:118491952..118491976 | 21/25 | Antisense | unknown | ||||
| Chr6L:53567307..53567331 | 21/25 | Antisense | unknown | tropicalis 10.0 | Chr1:155866727..155866751 | 24/25 | Sense | target | fbrsl1 |
| Chr2:122318038..122318062 | 21/25 | Antisense | off-target | dnajc3 | |||
| Chr8:85975326..85975350 | 21/25 | Antisense | off-target | zc3h14 | |||
| Chr3:112292850..112292874 | 21/25 | Sense | off-target | st8sia2 | |||
| Chr5:49987935..49987959 | 21/25 | Antisense | unknown | ||||
| Publications | |||||||
| ???morpholino.displaySummary.papersFirst??? |
De novo mutations in FBRSL1 cause a novel recognizable malformation and intellectual disability syndrome., Hum Genet 2020  |
||||||
| ???morpholino.displaySummary.papersRecent??? |
FBRSL1 regulates the expression of chromatin regulators BRPF1 and KAT6A., Hum Genet 2025  |
||||||
| ???morpholino.displaySummary.papersAll??? | |||||||
