Search Lines and Strains
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| Line Name | Species | Mutated Gene(s) | Description | Availability |
| Xtr.bicc1em2NXR | X. tropicalis | bicc1 | CRISPR mutant of bicc1 (BicC family RNA binding protein 1). Germline transmission has been confirmed... | |
| Xtr.bicc1em1NXR | X. tropicalis | bicc1 | CRISPR mutant of bicc1 (BicC family RNA binding protein 1). Germline transmission has been confirmed... | |
| Xtr.bhlhe22emHorb | X. tropicalis | bhlhe22 | CRISPR knockout of bhlhee2 (basic helix-loop-helix family member e22), Current mosaic founders, Conf... | |
| Xtr.bcorem4Horb | X. tropicalis | bcor | CRISPR knockout of bcor (BCL6 corepressor). Germline transmission confirmed. Mutation is a 11bp dele... | |
| Xtr.bcorem3Horb | X. tropicalis | bcor | CRISPR knockout of bcor (BCL6 corepressor). Germline transmission confirmed. Mutation is a 5bp delet... | |
| Xtr.bcorem2Horb | X. tropicalis | bcor | CRISPR knockout of bcor (BCL6 corepressor). Germline transmission confirmed. Mutation is a 1bp delet... | |
| Xtr.bcorem1Horb | X. tropicalis | bcor | CRISPR knockout of bcor (BCL6 corepressor). Germline transmission confirmed. Mutation is a 4bp delet... | |
| Xtr.bace1emHorb | X. tropicalis | bace1 | CRISPR knockout of bace1 (beta-site APP-cleaving enzyme 1), Current mosaic founders, Not tested for ... | |
| Xtr.atp7amZimml | X. tropicalis | atp7a | A mutation affecting retinal epithelium identified in the Mill Hill screen for ENU-induced mutations... | |
| Xtr.askmZimml | X. tropicalis | unknown | Mutation affecting the formation of inner ear otoconia identified in the Mill Hill screen for ENU-in... | |
| Xtr.ascl1emHorb | X. tropicalis | ascl1 | CRISPR knockout of ascl1(achaete-scute family bHLH transcription factor 1). Confirmed germline trans... | |
| Xtr.arnt,arnt2emHorb | X. tropicalis | arnt | CRISPR knockout of arnt/arnt2 (aryl hydrocarbon receptor nuclear translocator), Current mosaic found... | |
| Xtr.apcMRCΔ1/+Vlemx | X. tropicalis | apc | F0 apc mosaics generated by apc TALENs injection, were outcrossed with WT X. tropicalis, and offspri... | |
| Xtr.ap3d1mZimml | X. tropicalis | ap3d1 | Mutation affecting inner ear otoconia identified in the Mill Hill screen for ENU-induced mutations. ... | |
| Xtr.amhem3NXR | X. tropicalis | amh | CRISPR knockout of amh (anti-Mullerian hormone ). Confirmed germline transmission. Custom mutant gen... | |
| Xtr.amhem2NXR | X. tropicalis | amh | CRISPR knockout of amh (anti-Mullerian hormone ). Confirmed germline transmission. Custom mutant: 5b... | |
| Xtr.amhem1NXR | X. tropicalis | amh | CRISPR knockout of amh (anti-Mullerian hormone). Germline transmission confirmed. +8bp mutation in a... | |
| Xtr.amhr2emNXR | X. tropicalis | amhr2 | CRISPR knockout of amhr2 (anti-Mullerian hormone receptor type II ). Confirmed germline transmission... | |
| Xtr.aif1lem2Horb | X. tropicalis | aif1l | CRISPR knockout of aif1l (allograft inflammatory factor 1-like). Confirmed germline transmission. Cu... | |
| Xtr.aif1lem1Horb | X. tropicalis | aif1l | CRISPR knockout of aif1l (allograft inflammatory factor 1-like). Confirmed germline transmission. Cu... | |
| Xtr.ahrem2NXR | X. tropicalis | ahr | TALEN generated mutant line, made by the NXR. Germ line transmission confirmed. mutation: 7bp deleti... | |
| Xtr.ahrem1NXR | X. tropicalis | ahr | TALEN generated mutant line, made by the NXR. Germ line transmission confirmed. ,+2bp mutation: CCAT... | |
| Xtr.acsl1emNXR | X. tropicalis | acsl1 | CRISPR knockout of acsl1 (acyl-CoA synthetase long chain family member 1). Germ line transmission co... | |
| Xtr. lrrk2emNXR | X. tropicalis | lrrk2 | CRISPR knockout fo CRISPR knockout fo (leucine-rich repeat kinase 2 ). Germ line transmission confir... | |
| Xla.xdm-wemNXR | X. laevis | dm-w.L | CRISPR knock out of xdm-w (doublesex and mab3 related transcription factor W ). Germ Line transmissi... | |
| Xla.wnt11emHorb | X. laevis | wnt11.L | CRISPR knockout of wnt11 (Wnt family member 11), Confirmed germline transmission. Mutant line genera... | |
| Xla.wnt11bemNXR | X. laevis | wnt11b.L | CRISPR knockout of wnt11b in X laevis. Germline transmission confirmed. F2 animals carry a 13bp del... | |
| Xla.wdpcpemHorb | X. laevis | wdpcp.L | CRISPR knockout of wdpcp (WD repeat containing planar cell polarity effector). Germ line transmissio... | |
| Xla.tyremNXR | X. laevis | tyr.L | TALEN induced tyrosinase mutant. Custom line made by the NXR. Contact NXR for details. | |
| Xla.trilemNXR | X. laevis | tril.L | CRISPR knockout of tril (LR4 interactor with leucine-rich repeats). Co-injected for both L and S. Ge... | |
| Xla.thrbem3NXR | X. laevis | thrb.L | Double CRISPR mutant line of thrb (thyroid hormone receptor, beta ) with animals carrying a 8bp dele... | |
| Xla.thrbem2NXR | X. laevis | thrb.S | CRISPR knockout of thrb.S thyroid hormone receptor, beta S homolog). germline transmission confirmed... | |
| Xla.thrbem1NXR | X. laevis | thrb.L | CRISPR knockout of thrb.L thyroid hormone receptor, beta L homolog). germline transmission confirmed... | |
| Xla.tcf3em2NXR | X. laevis | CRISPR knockout of tcf3.S ( transcription factor 3). Germ line transmission not yet confirmed. Cont... | ||
| Xla.sox10emHorb | X. laevis | sox10.L | CRISPR knockout of sox10 (SRY-box 10). Confirmed germline transmission in sox10.L (waiting for confi... | |
| Xla.sobpemNXR | X. tropicalis | sobp | CRISPR knockout of sobp (sine oculis binding protein homolog ), a gene associated with MRAMS, an in... | |
| Xla.slc45a2emNXR | X. laevis | slc45a2.L | ||
| Xla.slc45a2em2NXR | X. laevis | slc45a2.L | CRISPR knockout of slc45a2 (solute carrier family 45 member 2 ). Screened for germline transmission.... | |
| Xla.slc45a1emNXR | X. laevis | slc45a1.L | CRISPR knockout of Slc45a1 (solute carrier family 45 member 1 ). Screened for germline transmission.... | |
| Xla.slc16a2emHorb | X. laevis | slc16a2.L | CRISPR knockout of slc16a2 (solute carrier family 16, member 2 (thyroid hormone transporter)). Germ ... | |
| Xla.ryk.SemNXR | X. laevis | CRISPR knockout of ryk.S (receptor like tyrosine kinase S homeolog). Germline transmission not yet c... | ||
| Xla.runx1em(GFP)EXRC | X. laevis | runx1.L | CRISPR-Cas9 mediated insertion of IRES-GFP sequence into the 3'-UTR of runx1 gene, | |
| Xla.rag2emNXR | X. laevis | CRISPR knockout of rag2 (recombination activating 2). Germ line transmission confirmed. Animals carr... | ||
| Xla.prph2emHorb | X. laevis | prph2.L | CRISPR knockout of prph2 (peripherin 2 (retinal degeneration, slow)). Current mosaic founders, not t... | |
| Xla.prkdcem2NXR | X. laevis | CRISPR KO of prkdc (protein kinase, DNA-activated, catalytic subunit ). Germ line transmission confi... | ||
| Xla.prkdcem1NXR | X. laevis | prkdc.L | CRISPR KO of prkdc (protein kinase, DNA-activated, catalytic subunit ). Germ line transmission confi... | |
| Xla.prickle1emHorb | X. laevis | prickle1.L | CRISPR knockout of prickle1(prickle planar cell polarity protein 1). Confirmed germ line transmissio... | |
| Xla.ppp2r2aemHorb | X. laevis | ppp2r2a.L | CRISPR knockout of ppp2r2a (protein phosphatase 2 regulatory subunit B, alpha ). Current mosaic foun... | |
| Xla.pkhd1emHorb | X. laevis | pkhd1.L | CRISPR knockout of pkhd1 (PKHD1, fibrocystin/polyductin), Germ line transmission confirmed. Animals ... | |
| Xla.pkd2emHorb | X. laevis | pkd2.L | CRISPR knockout of pkd2 (polycystin 2, transient receptor potential cation channel ). Confirmed germ... |
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