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Line Name Species Mutated Gene(s) Description Availability
Xtr.mtnr1aemNXR X. tropicalis mtnr1a CRISPR knock out of mtnr1a (melatonin receptor 1A ) in X. tropicalis. germ line transmission confirm... NXR
Xtr.six1em2NXR X. tropicalis six1 CRISPR knockout of six1 (SIX homeobox 1), a gene associated with branchiootorenal syndrome and branc...
Xtr.zmym4emNXR X. tropicalis zmym4 CRISPR KO of zmym4 (zinc finger MYM-type containing 4) in X. tropicalis. Germline transmission confi...
Xtr.zeb2emNXR X. tropicalis zeb2 CRISPR KO of zeb2 (zinc finger E-box binding homeobox 2), a gene associated with Mowat-Wilson syndro...
Xtr.ywhazemNXR X. tropicalis ywhaz CRISPR KO of ywhaz (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta). ge...
Xtr.xbp1emNXR X. tropicalis xbp1 CRISPR KO of xbp1 ( X-box binding protein 1 ) a gene assocaited with Major Affected Disorder in huma...
Xla.baz1bemNXR X. laevis baz1b.L TALENs knockout of baz1b (bromodomain adjacent to zinc finger domain 1B ) aka wstf,a gene associated...
Xla.wnt11bemNXR X. laevis wnt11b.L CRISPR knockout of wnt11b in X laevis. Germline transmission confirmed. F2 animals carry a 13bp del...
Xtr.wnt11bemNXR X. tropicalis wnt11b CRISPR knockout of wnt11b (wingless-type MMTV integration site family, member 11B ), Germ line tran...
Xtr.wbp11emNXR X. tropicalis wbp11 CRISPR knockout of wbp11 (WW domain binding protein 11). Germline transmission confirmed, F2s growin...
Xtr.vwa2emNXR X. tropicalis vwa2 CRISPR knock out of vwa2 (von Willebrand factor A domain containing 2 ). Germ line transmission conf...
Xtr.vangl2emNXR X. tropicalis vangl2 CRISPR knockout of vangl2 (VANGL planar cell polarity protein 2 ), a gene associated with neural tub...
Xtr.tspan8em3Horb X. tropicalis tspan8 CRISPR knockout of tspan8 (tetraspanin 8), Germ line transmission confirmed. 3rd of 3 tspan lines at...
Xtr.tspan8em2Horb X. tropicalis tspan8 CRISPR knockout of tspan8 (tetraspanin 8), Germ line transmission confirmed. 2nd of 3 tspan lines at...
Xla.trilemNXR X. laevis tril.L CRISPR knockout of tril (LR4 interactor with leucine-rich repeats). Co-injected for both L and S. Ge...
Xla.thrbem3NXR X. laevis thrb.L Double CRISPR mutant line of thrb (thyroid hormone receptor, beta ) with animals carrying a 8bp dele...
Xla.thrbem2NXR X. laevis thrb.S CRISPR knockout of thrb.S thyroid hormone receptor, beta S homolog). germline transmission confirmed...
Xla.thrbem1NXR X. laevis thrb.L CRISPR knockout of thrb.L thyroid hormone receptor, beta L homolog). germline transmission confirmed...
Xtr.tdrd1emNXR X. tropicalis tdrd1 CRISPR knockout of tdrd1 (tudor domain containing 1). Germline transmission not yet confirmed. growi...
Xtr.srd5a3emNXR X. tropicalis srd5a3 CRISPR knockout of srd5a3 (steroid 5 alpha-reductase 3), Germ line transmission confirmed. F1 growin...

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