Search Lines and Strains
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| Line Name | Species | Mutated Gene(s) | Description | Availability |
| Xla.mcidasemHorb | X. laevis | mcidas.L | CRISPR knockout of mcidas (multiciliate differentiation and DNA synthesis associated cell cycle prot... | |
| Xla.notch4emHorb | X. laevis | notch4.S | TALEN knockout of notch4 in X. laevis. THIS LINE is no longer available from the NXR | |
| Xla.olig2emHorb | X. laevis | olig2.L | CRISPR knockout of olig2 (oligodendrocyte lineage transcription factor 2) in X. laevis. KOs both oli... | |
| Xla.wdpcpemHorb | X. laevis | wdpcp.L | CRISPR knockout of wdpcp (WD repeat containing planar cell polarity effector). Germ line transmissio... | |
| Xla.wnt11emHorb | X. laevis | wnt11.L | CRISPR knockout of wnt11 (Wnt family member 11), Confirmed germline transmission. Mutant line genera... | |
| Xtr.raxmGrngr | X. tropicalis | rax | This mutant line was generated in an ENU screen from the Grainger lab by TILLING (Targeting Induced ... | |
| Xtr.tyremNXR | X. tropicalis | tyr | CRISPR knockout of tyr (tyrosinase), Confirmed germline transmission. Animal carry a 241bp insertion... | |
| Xtr.tbx5emHorb | X. tropicalis | tbx5 | CRISPR knockout of tbx5 (T-box 5 ), Confirmed germline transmission. Custom mutant generated by Horb... | |
| Xtr.fibinemHorb | X. tropicalis | fibin | CRISPR knockout of fibin (fin bud initiation factor homolog), Confirmed germline transmission. Custo... | |
| Xtr.kng1emHorb | X. tropicalis | kng1 | CRISPR knockout of kng1 (kininogen 1), Germline transmission confirmed. Mutants carry a bp deletion ... | |
| Xtr.bhlhe22emHorb | X. tropicalis | bhlhe22 | CRISPR knockout of bhlhee2 (basic helix-loop-helix family member e22), Current mosaic founders, Conf... | |
| Xla.hmgcremHorb | X. laevis | hmgcr.L | CRISPR knockout of hmgcr (3-hydroxy-3-methylglutaryl-CoA reductase). Germline transmission confirmed... | |
| Xtr.runx1t1emHorb | X. tropicalis | runx1t1 | CRISPR knockout of runx1t1(RUNX1 partner transcriptional co-repressor 1) gene. Germ line transmissio... | |
| Xtr.tlx3em2Horb | X. tropicalis | tlx3 | CRISPR mutant line targeting tlx3 (T cell leukemia homeobox 3). Germ lIne transmission was confirmed... | |
| Xtr.notch4emHorb | X. tropicalis | notch4 | CRISPR knockout of notch4 in X. tropicalis. Confirmed germline transmission. Mutation characterized:... | |
| Xtr.zbtb14emHorb | X. tropicalis | zbtb14 | CRISPR knockout of zbtb14 (zinc finger and BTB domain containing 14). Germ line transmission confirm... | |
| Xtr.tbx2emHorb | X. tropicalis | tbx2 | CRISPR knockout of tbx2 (T-box 2), Current mosaic founders, Not tested for germline transmission. | |
| Xtr.ezh2emHorb | X. tropicalis | ezh2 | CRISPR knockout of ezh2 (enhancer of zeste 2 polycomb repressive complex 2 subunit), Germ line trans... | |
| Xtr.sox3emHorb | X. tropicalis | sox3 | CRISPR knockout of sox3 (SRY-box 3), Current mosaic founders, Not tested for germline transmission. ... | |
| Xtr.icam5emHorb | X. tropicalis | icam5 | CRISPR knockout of icam5 (intercellular adhesion molecule 5), Germ line transmission confirmed. Cust... |
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