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Results 51 - 98 of 98 results

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Line Name Species Mutated Gene Description Availability
Xtr.hps6mGrngr

X.tropicalis hps6 No Privacy (NOP) embryos have a 10-bp deletion in the hps6 gene (a region from 468 to 477 counted fr... NXR EXRC
Xtr.glis3emHorb

X.tropicalis glis3 CRISPR knockout of glis3 (GLIS family zinc finger 3). Confirmed germline transmission. Custom mutant... NXR
Xtr.gfi1emHorb

X.tropicalis gfi1 CRISPR knockout of gfi1 (growth factor independent 1 transcription repressor). Not screened for germ... NXR
Xtr.gdf1emHorb

X.tropicalis gdf1 CRISPR knockout of gdf1 (growth differentiation factor 1). Confirmed germline transmission. Custom ... NXR
Xtr.frzb,frzb2emHorb

X.tropicalis frzb2 double CRISPR knockout of frzb (frizzled related protein ) and frzb2 (frizzled related protein 2). C... NXR
Xtr.foxc2emHorb

X.tropicalis foxc2 CRISPR knockout of foxc2 (forkhead box C2). Confirmed germline transmission. Custom mutant generate... NXR
Xtr.foxb1emHorb

X.tropicalis foxb1 CRISPR knockout of foxb1 (forkhead box B1 ), Current mosaic founders, Not tested for germline transm... NXR
Xtr.ezh2emHorb

X.tropicalis ezh2 CRISPR knockout of ezh2 (enhancer of zeste 2 polycomb repressive complex 2 subunit), Current mosaic ... NXR
Xtr.erfemHorb

X.tropicalis erf CRISPR knockout of erf (ETS2 repressor factor). Confirmed germline transmission. Custom mutant gene... NXR
Xtr.eomesemHorb

X.tropicalis eomes CRISPR knockout of eomes (eomesodermin), Current mosaic founders, Not tested for germline transmissi... NXR
Xtr.dtlemHorb

X.tropicalis dtl CRISPR knockout of dtl (denticleless E3 ubiquitin protein ligase homolog), Current mosaic founders, ... NXR
Xtr.dstmZimml

X.tropicalis unknown Mutation affecting the haematopoietic system identified in the Mill Hill screen for ENU-induced muta... EXRC
Xtr.bxemZimml

X.tropicalis unknown Mutation affecting eye development identified in the Mill Hill screen for ENU-induced mutations. EXRC
Xtr.bunmZimml

X.tropicalis unknown Mutation affecting the ear development identified in the Mill Hill screen for ENU-induced mutations. EXRC
Xtr.bhlhe22emHorb

X.tropicalis bhlhe22 CRISPR knockout of bhlhee2 (basic helix-loop-helix family member e22), Current mosaic founders, Conf... NXR
Xtr.bcoremHorb

X.tropicalis bcor CRISPR knockout of bcor (BCL6 corepressor). Not screened for germline transmission. NXR
Xtr.bace1emHorb

X.tropicalis bace1 CRISPR knockout of bace1(beta-site APP-cleaving enzyme 1), Current mosaic founders, Not tested for g... NXR
Xtr.atp7amZimml

X.tropicalis atp7a A mutation affecting retinal epithelium identified in the Mill Hill screen for ENU-induced mutations... EXRC
Xtr.askmZimml

X.tropicalis unknown Mutation affecting the formation of inner ear otoconia identified in the Mill Hill screen for ENU-in... EXRC
Xtr.ascl1emHorb

X.tropicalis ascl1 CRISPR knockout of ascl1(achaete-scute family bHLH transcription factor 1). Confirmed germline trans... NXR
Xtr.arnt,arnt2emHorb

X.tropicalis arnt CRISPR knockout of arnt/arnt2 (aryl hydrocarbon receptor nuclear translocator), Current mosaic found... NXR
Xtr.ap3d1mZimml

X.tropicalis ap3d1 Mutation affecting inner ear otoconia identified in the Mill Hill screen for ENU-induced mutations. ... EXRC
Xtr.aif1lemHorb

X.tropicalis aif1l CRISPR knockout of aif1l (allograft inflammatory factor 1-like). Confirmed germline transmission. Cu... NXR
Xla.wnt11emHorb

X.laevis wnt11.L CRISPR knockout of wnt11 (Wnt family member 11 ), Confirmed germline transmission. Mutant line gener... NXR
Xla.wdpcpemHorb

X.laevis wdpcp.L CRISPR knockout of wdpcp (WD repeat containing planar cell polarity effector). Current mosaic founde... NXR
Xla.tyremNXR

X.laevis tyr.L TALEN induced tyrosinase mutant. Custom line made by the NXR. NXR
Xla.sox10emHorb

X.laevis sox10.L CRISPR knockout of sox10 (SRY-box 10). Confirmed germline transmission. Mutant line generated by Hor... NXR
Xla.slc45a1emNXR

X.laevis slc45a1.L CRISPR knockout of Slc45a2 (solute carrier family 45 member 1 ). Screened for germline transmission.... NXR
Xla.slc16a2emHorb

X.laevis slc16a2.L CRISPR knockout of slc16a2 (solute carrier family 16, member 2 (thyroid hormone transporter)). Curre... NXR
Xla.runx1em(GFP)EXRC

X.laevis runx1.L CRISPR-Cas9 mediated insertion of IRES-GFP sequence into the 3'-UTR of runx1 gene, EXRC
Xla.prph2emHorb

X.laevis prph2.L CRISPR knockout of prph2 (peripherin 2 (retinal degeneration, slow)). Current mosaic founders, not t... NXR
Xla.prickle1emHorb

X.laevis prickle1.L CRISPR knockout of prickle1(prickle planar cell polarity protein 1). Confirmed germline transmission... NXR
Xla.ppp2r2aemHorb

X.laevis ppp2r2a.L CRISPR knockout of ppp2r2a (protein phosphatase 2 regulatory subunit B, alpha ). Current mosaic foun... NXR
Xla.pkhd1emHorb

X.laevis pkhd1.L CRISPR knockout of pkhd1 (PKHD1, fibrocystin/polyductin), Current mosaic founders. Not screened for ... NXR
Xla.pkd2emHorb

X.laevis pkd2.L CRISPR knockout of pkd2 (polycystin 2, transient receptor potential cation channel ). Confirmed germ... NXR
Xla.pkd1emHorb

X.laevis pkd1.L CRISPR knockout of pkd1 (polycystin 1, transient receptor potential channel interacting). Current m... NXR
Xla.pcntemHorb

X.laevis pcnt.L CRISPR knockout of pcnt (pericentrin ). Confirmed germline transmission. Custom mutant generated by ... NXR
Xla.pax7emHorb

X.laevis pax7.L CRISPR knockout of pax7 (paired box 7 ). Current mosaic founders, not tested for germline transmissi... NXR
Xla.pax3emHorb

X.laevis pax3.L CRISPR knockout of pax3 (paired box 3). Current mosaic founders, not tested for germline transmissio... NXR
Xla.olig3emHorb

X.laevis olig3.S CRISPR knockout of olig3 (oligodendrocyte transcription factor 3). Current mosaic founders, not test... NXR
Xla.olig2emHorb

X.laevis olig2.L CRISPR knockout of olig2 (oligodendrocyte lineage transcription factor 2). Current mosaic founders. ... NXR
Xla.npffr1.1emEXRC

X.laevis npffr1.1.L Crispr-Cas9 mutation in the npffr1.1 gene (neuropeptide FF receptor 1, gene 1 ). EXRC
Xla.mitfemHorb

X.laevis mitf.L CRISPR knockout of mitf (melanocyte inducing transcription factor) Currently mosaic founders. Not sc... NXR
Xla.mcidasemHorb

X.laevis mcidas.L CRISPR knockout of mcidas. Current mosaic founders. Not screened for germline transmission. Gene loc... NXR
Xla.gfi1emHorb

X.laevis gfi1.L CRISPR knockout of gfi1 (growth factor independent 1 transcription repressor ).Confirmed germline tr... NXR
Xla.fxr1emHorb

X.laevis fxr1.L CRISPR Knockout of fxr1(FMR1 autosomal homolog 1 ). Currently mosaic founders. Confirmed germline tr... NXR
Xla.eya1emHorb

X.laevis eya1.L CRISPR Knockout of eya1. Currently mosaic founders. not screened for germline transmission. Mutant l... NXR
Xla.aqpemHorb

X.laevis aqp1.L CRISPR Knockout of Aquaporin1. Currently mosaic founders. not screened for germline transmission. Mu... NXR

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