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Line Name Species Mutated Gene(s) Description Availability
Xtr.amhem1NXR X. tropicalis amh CRISPR knockout of amh (anti-Mullerian hormone). Germline transmission confirmed. +8bp mutation in a...
Xtr.wwoxemHorb X. tropicalis wwox CRISPR knockout of wwox (WW domain containing oxidoreductase), a gene associated with esophageal can...
Xtr.runx2emHorb X. tropicalis runx2 CRISPR knockout of runx2 (runt related transcription factor 2). Contact NXR to inquire about availab...
Xtr.legmZimml X. tropicalis unknown Mutation affecting otoconia formation identified in the Mill Hill screen of ENU-induced mutations.
Xtr.tupmZimml X. tropicalis unknown Mutation affecting axial development identified in the Mill Hill screen of ENU-induced mutations.
Xtr.dstmZimml X. tropicalis unknown Mutation affecting the haematopoietic system identified in the Mill Hill screen for ENU-induced muta...
Xtr.bunmZimml X. tropicalis unknown Mutation affecting the ear development identified in the Mill Hill screen for ENU-induced mutations.
Xtr.bxemZimml X. tropicalis unknown Mutation affecting eye development identified in the Mill Hill screen for ENU-induced mutations.
Xtr.mammZimml X. tropicalis unknown Mutation affecting cardiac function identified in a screen for ENU-induced mutations at Mill Hill
Xtr.askmZimml X. tropicalis unknown Mutation affecting the formation of inner ear otoconia identified in the Mill Hill screen for ENU-in...
Xtr.smad4mZimml X. tropicalis smad4 Mutation affecting haematopoiesis identified in a screen for ENU-induced mutations at Mill Hill. Pos...
Xtr.unc45bmZimml X. tropicalis unc45b Mutation affecting striated muscle identified in the Mill Hill screen for ENU-induced mutations.
Xtr.mlomZimml X. tropicalis unknown Mutation affecting striated muscle identified in the Mill Hill screen for ENU-induced mutations. Map...
Xtr.petmZimml X. tropicalis unknown Homozygous mutants are completely paralyzed with no heartbeat.
Xtr.supt5hmZimml X. tropicalis supt5h Mutation affecting eye development and melanophore migration identified in the Mill Hill screen for ...
Xtr.atp7amZimml X. tropicalis atp7a A mutation affecting retinal epithelium identified in the Mill Hill screen for ENU-induced mutations...
Xtr.ap3d1mZimml X. tropicalis ap3d1 Mutation affecting inner ear otoconia identified in the Mill Hill screen for ENU-induced mutations. ...
Xtr.oc90mZimml X. tropicalis oc90 Mutation affecting inner ear otoconia identified in the Mill Hill screen for ENU-induced mutations. ...
Xtr.tbxtemJcsm X. tropicalis tbxt Talen-induced 2bp deletion in exon 1 of tbxt (T-box transcription factor T) gene. Mutation destroys ...
Xla.npffr1.1emEXRC X. laevis npffr1.1.L Crispr-Cas9 mutation in the npffr1.1 gene (neuropeptide FF receptor 1, gene 1 ).

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