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Results 1 - 50 of 98 results

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Line Name Species Mutated Gene Description Availability
Xla.runx1em(GFP)EXRC

X.laevis runx1.L CRISPR-Cas9 mediated insertion of IRES-GFP sequence into the 3'-UTR of runx1 gene, EXRC
Xtr.tbxt,tbxt.2emJcsm

X.tropicalis tbxt Double talen-induced mutant line. Talen induced 2-bp deletion in exon 1 of tbxt and 7 bp deletion in... EXRC
Xtr.tbxt.2em2Jcsm

X.tropicalis tbxt.2 Talen-induced mutant line. Talen-induced 7-bp deletion in third exon of T, brachyury homolog, gene ... EXRC
Xtr.tbxt.2em1Jcsm

X.tropicalis tbxt.2 Talen-mediated mutant line. Talen-induced 7-bp deletion in third exon of T, brachyury homolog, gene ... EXRC
Xla.npffr1.1emEXRC

X.laevis npffr1.1.L Crispr-Cas9 mutation in the npffr1.1 gene (neuropeptide FF receptor 1, gene 1 ). EXRC
Xtr.tbxtemJcsm

X.tropicalis tbxt Talen-induced 2bp deletion in exon 1 of tbxt (T-box transcription factor T) gene. Mutation destroys ... EXRC
Xtr.oc90mZimml

X.tropicalis oc90 Mutation affecting inner ear otoconia identified in the Mill Hill screen for ENU-induced mutations. ... EXRC
Xtr.ap3d1mZimml

X.tropicalis ap3d1 Mutation affecting inner ear otoconia identified in the Mill Hill screen for ENU-induced mutations. ... EXRC
Xtr.atp7amZimml

X.tropicalis atp7a A mutation affecting retinal epithelium identified in the Mill Hill screen for ENU-induced mutations... EXRC
Xtr.supt5hmZimml

X.tropicalis supt5h Mutation affecting eye development and melanophore migration identified in the Mill Hill screen for ... EXRC
Xtr.petmZimml

X.tropicalis unknown Homozygous mutants are completely paralyzed with no heartbeat. EXRC
Xtr.mlomZimml

X.tropicalis unknown Mutation affecting striated muscle identified in the Mill Hill screen for ENU-induced mutations. Map... EXRC
Xtr.unc45bmZimml

X.tropicalis unc45b Mutation affecting striated muscle identified in the Mill Hill screen for ENU-induced mutations. EXRC
Xtr.smad4.1mZimml

X.tropicalis smad4.1 Mutation affecting haematopoiesis identified in a screen for ENU-induced mutations at Mill Hill. Pos... EXRC
Xtr.askmZimml

X.tropicalis unknown Mutation affecting the formation of inner ear otoconia identified in the Mill Hill screen for ENU-in... EXRC
Xtr.bxemZimml

X.tropicalis unknown Mutation affecting eye development identified in the Mill Hill screen for ENU-induced mutations. EXRC
Xtr.mammZimml

X.tropicalis unknown Mutation affecting cardiac function identified in a screen for ENU-induced mutations at Mill Hill EXRC
Xtr.bunmZimml

X.tropicalis unknown Mutation affecting the ear development identified in the Mill Hill screen for ENU-induced mutations. EXRC
Xtr.dstmZimml

X.tropicalis unknown Mutation affecting the haematopoietic system identified in the Mill Hill screen for ENU-induced muta... EXRC
Xtr.tupmZimml

X.tropicalis unknown Mutation affecting axial development identified in the Mill Hill screen of ENU-induced mutations. EXRC
Xtr.legmZimml

X.tropicalis unknown Mutation affecting otoconia formation identified in the Mill Hill screen of ENU-induced mutations. EXRC
Xtr.runx2emHorb

X.tropicalis runx2 CRISPR knockout of runx2 (runt related transcription factor 2). This mutation is lethal during metam... NXR
Xtr.wwoxemHorb

X.tropicalis wwox CRISPR knockout of wwox (WW domain containing oxidoreductase). Not screened for germline transmissio... NXR
Xtr.gfi1emHorb

X.tropicalis gfi1 CRISPR knockout of gfi1 (growth factor independent 1 transcription repressor). Not screened for germ... NXR
Xtr.sox2emHorb

X.tropicalis sox2 CRISPR knockout of sox2 (SRY-box 2). Not screened for germline transmission. NXR
Xtr.otx2emHorb

X.tropicalis otx2 CRISPR knockout of otx2 (orthodenticle homeobox 2). Not screened for germline transmission. NXR
Xtr.kcnj8emHorb

X.tropicalis kcnj8 CRISPR knockout of kcnj8 (potassium channel, inwardly rectifying subfamily J, member 8). Not screene... NXR
Xtr.bcoremHorb

X.tropicalis bcor CRISPR knockout of bcor (BCL6 corepressor). Not screened for germline transmission. NXR
Xtr.nhlh1emHorb

X.tropicalis nhlh1 CRISPR knockout of nhlh1 (nescient helix-loop-helix 1). Not screened for germline transmission. NXR
Xtr.wt1emHorb

X.tropicalis wt1 CRISPR knockout of wt1 (Wilms tumor 1). Not screened for germline transmission. NXR
Xla.pkhd1emHorb

X.laevis pkhd1.L CRISPR knockout of pkhd1 (PKHD1, fibrocystin/polyductin), Current mosaic founders. Not screened for ... NXR
Xla.pkd1emHorb

X.laevis pkd1.L CRISPR knockout of pkd1 (polycystin 1, transient receptor potential channel interacting). Current m... NXR
Xtr.foxb1emHorb

X.tropicalis foxb1 CRISPR knockout of foxb1 (forkhead box B1 ), Current mosaic founders, Not tested for germline transm... NXR
Xtr.dtlemHorb

X.tropicalis dtl CRISPR knockout of dtl (denticleless E3 ubiquitin protein ligase homolog), Current mosaic founders, ... NXR
Xtr.myt1emHorb

X.tropicalis myt1 CRISPR knockout of myt1 (myelin transcription factor 1). Not tested for germline transmission. NXR
Xtr.eomesemHorb

X.tropicalis eomes CRISPR knockout of eomes (eomesodermin), Current mosaic founders, Not tested for germline transmissi... NXR
Xtr.arnt,arnt2emHorb

X.tropicalis arnt CRISPR knockout of arnt/arnt2 (aryl hydrocarbon receptor nuclear translocator), Current mosaic found... NXR
Xtr.shroom3emHorb

X.tropicalis shroom3 CRISPR knockout of shroom3 (shroom family member 3), Current mosaic founders, Not tested for germlin... NXR
Xtr.zbtb21emHorb

X.tropicalis zbtb21 CRISPR knockout of zbtb21(zinc finger and BTB domain containing 21), Current mosaic founders, Not te... NXR
Xtr.tspan8emHorb

X.tropicalis tspan8 CRISPR knockout of tspan8 (tetraspanin 8), Current mosaic founders, Not tested for germline transmis... NXR
Xtr.bace1emHorb

X.tropicalis bace1 CRISPR knockout of bace1(beta-site APP-cleaving enzyme 1), Current mosaic founders, Not tested for g... NXR
Xtr.junbemHorb

X.tropicalis junb CRISPR knockout of junb (jun B proto-oncogene), Current mosaic founders, Not tested for germline tra... NXR
Xtr.sox3emHorb

X.tropicalis sox3 CRISPR knockout of sox3 (SRY-box 3), Current mosaic founders, Not tested for germline transmission. ... NXR
Xtr.ezh2emHorb

X.tropicalis ezh2 CRISPR knockout of ezh2 (enhancer of zeste 2 polycomb repressive complex 2 subunit), Current mosaic ... NXR
Xtr.tbx2emHorb

X.tropicalis tbx2 CRISPR knockout of tbx2 (T-box 2), Current mosaic founders, Not tested for germline transmission. NXR
Xtr.zbtb14emHorb

X.tropicalis zbtb14 CRISPR knockout of zbtb14 (zinc finger and BTB domain containing 14). Germ line transmission not yet... NXR
Xtr.notch4emHorb

X.tropicalis notch4 CRISPR knockout of notch4. Confirmed germline transmission. NXR
Xtr.tlx3em2Horb

X.tropicalis tlx3 2nd CRISPR mutant line targeting tlx3 (T cell leukemia homeobox 3). Germ lIne transmission confirmed... NXR
Xtr.runx1t1emHorb

X.tropicalis runx1t1 CRISPR knockout of runx1t1( RUNX1 translocation partner 1) gene. Germ line transmission not yet conf... NXR
Xtr.bhlhe22emHorb

X.tropicalis bhlhe22 CRISPR knockout of bhlhee2 (basic helix-loop-helix family member e22), Current mosaic founders, Conf... NXR

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