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Results 1 - 50 of 79 results

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Line Name Species Mutated Gene Description Availability
Xtr.tp53em_del1/em_del2_Vlemx

X.tropicalis tp53 Two types of F1 tp53 heterozygotes, each with a distinct variant of a deletion (em_del1/+ and em_del...
Xla.hps4m

X.laevis hps4.L This periodic albino mutant of Xenopus laevis is a recessive mutant. Fukazawa et al 2020 showed that...
Xtr.tp53em_del2/+_Vlemx

X.tropicalis tp53 Deletion is expected to give rise to nonsense-mediated decay since due to the frame-shifting deletio...
Xtr.tp53em_del1/+_Vlemx

X.tropicalis tp53 Deletion is expected to give rise to nonsense-mediated decay since due to the frame-shifting deleti...
Xtr.tbxt,tbxt.2emJcsm

X.tropicalis tbxt Double talen-induced mutant line. Talen induced 2-bp deletion in exon 1 of tbxt and 7 bp deletion in... EXRC
Xtr.tbxt.2em2Jcsm

X.tropicalis tbxt.2 Talen-induced mutant line. Talen-induced 7-bp deletion in third exon of T, brachyury homolog, gene ... EXRC
Xtr.tbxt.2em1Jcsm

X.tropicalis tbxt.2 Talen-mediated mutant line. Talen-induced 7-bp deletion in third exon of T, brachyury homolog, gene ... EXRC
Xla.npffr1.1emEXRC

X.laevis npffr1.1.L Crispr-Cas9 mutation in the npffr1.1 gene (neuropeptide FF receptor 1, gene 1 ). EXRC
Xtr.tbxtemJcsm

X.tropicalis tbxt Talen-induced 2bp deletion in exon 1 of tbxt (T-box transcription factor T) gene. Mutation destroys ... EXRC
Xtr.smad4.1mZimml

X.tropicalis smad4 Mutation affecting haematopoiesis identified in a screen for ENU-induced mutations at Mill Hill. Pos... EXRC
Xtr.dstmZimml

X.tropicalis unknown Mutation affecting the haematopoietic system identified in the Mill Hill screen for ENU-induced muta... EXRC
Xtr.tupmZimml

X.tropicalis unknown Mutation affecting axial development identified in the Mill Hill screen of ENU-induced mutations. EXRC
Xtr.legmZimml

X.tropicalis unknown Mutation affecting otoconia formation identified in the Mill Hill screen of ENU-induced mutations. EXRC
Xtr.nhlh1emHorb

X.tropicalis nhlh1 CRISPR knockout of nhlh1 (nescient helix-loop-helix 1). Not screened for germline transmission. NXR
Xtr.wt1emHorb

X.tropicalis wt1 CRISPR knockout of wt1 (Wilms tumor 1). Not screened for germline transmission. NXR
Xtr.foxb1emHorb

X.tropicalis foxb1 CRISPR knockout of foxb1 (forkhead box B1 ), Current mosaic founders, Not tested for germline transm... NXR
Xtr.dtlemHorb

X.tropicalis dtl CRISPR knockout of dtl (denticleless E3 ubiquitin protein ligase homolog), Current mosaic founders, ... NXR
Xtr.myt1emHorb

X.tropicalis myt1 CRISPR knockout of myt1 (myelin transcription factor 1). Not tested for germline transmission. NXR
Xtr.eomesemHorb

X.tropicalis eomes CRISPR knockout of eomes (eomesodermin), Current mosaic founders, Not tested for germline transmissi... NXR
Xtr.arnt,arnt2emHorb

X.tropicalis arnt CRISPR knockout of arnt/arnt2 (aryl hydrocarbon receptor nuclear translocator), Current mosaic found... NXR
Xtr.shroom3emHorb

X.tropicalis shroom3 CRISPR knockout of shroom3 (shroom family member 3), Current mosaic founders, Not tested for germlin... NXR
Xtr.zbtb21emHorb

X.tropicalis zbtb21 CRISPR knockout of zbtb21(zinc finger and BTB domain containing 21), Current mosaic founders, Not te... NXR
Xtr.tspan8emHorb

X.tropicalis tspan8 CRISPR knockout of tspan8 (tetraspanin 8), Current mosaic founders, Not tested for germline transmis... NXR
Xtr.bace1emHorb

X.tropicalis bace1 CRISPR knockout of bace1(beta-site APP-cleaving enzyme 1), Current mosaic founders, Not tested for g... NXR
Xtr.junbemHorb

X.tropicalis junb CRISPR knockout of junb (jun B proto-oncogene), Current mosaic founders, Not tested for germline tra... NXR
Xtr.sox3emHorb

X.tropicalis sox3 CRISPR knockout of sox3 (SRY-box 3), Current mosaic founders, Not tested for germline transmission. ... NXR
Xtr.ezh2emHorb

X.tropicalis ezh2 CRISPR knockout of ezh2 (enhancer of zeste 2 polycomb repressive complex 2 subunit), Current mosaic ... NXR
Xtr.tbx2emHorb

X.tropicalis tbx2 CRISPR knockout of tbx2 (T-box 2), Current mosaic founders, Not tested for germline transmission. NXR
Xtr.zbtb14emHorb

X.tropicalis zbtb14 CRISPR knockout of zbtb14 (zinc finger and BTB domain containing 14). Germ line transmission not yet... NXR
Xtr.notch4emHorb

X.tropicalis notch4 CRISPR knockout of notch4. Confirmed germline transmission. NXR
Xtr.tlx3em2Horb

X.tropicalis tlx3 2nd CRISPR mutant line targeting tlx3 (T cell leukemia homeobox 3). Germ lIne transmission confirmed... NXR
Xtr.runx1t1emHorb

X.tropicalis runx1t1 CRISPR knockout of runx1t1( RUNX1 translocation partner 1) gene. Germ line transmission not yet conf... NXR
Xtr.bhlhe22emHorb

X.tropicalis bhlhe22 CRISPR knockout of bhlhee2 (basic helix-loop-helix family member e22), Current mosaic founders, Conf... NXR
Xtr.kng1emHorb

X.tropicalis kng1 CRISPR knockout of kng1(kininogen 1), Current mosaic founders, Not tested for germline transmission.... NXR
Xtr.tbx5emHorb

X.tropicalis tbx5 CRISPR knockout of tbx5 (T-box 5 ), Confirmed germline transmission. Custom mutant generated by Horb... NXR
Xtr.tyremNXR

X.tropicalis tyr CRISPR knockout of tyr (tyrosinase), Confirmed germline transmission. Custom mutant generated by the... NXR
Xtr.raxmGrngr

X.tropicalis rax This mutant line was generated in an ENU screen from the Grainger lab by TILLING (Targeting Induced ... NXR
Xla.wnt11emHorb

X.laevis wnt11.L CRISPR knockout of wnt11 (Wnt family member 11 ), Confirmed germline transmission. Mutant line gener... NXR
Xla.wdpcpemHorb

X.laevis wdpcp.L CRISPR knockout of wdpcp (WD repeat containing planar cell polarity effector). Current mosaic founde... NXR
Xla.olig2emHorb

X.laevis olig2.L CRISPR knockout of olig2 (oligodendrocyte lineage transcription factor 2). Current mosaic founders. ... NXR
Xla.mcidasemHorb

X.laevis mcidas.L CRISPR knockout of mcidas. Current mosaic founders. Not screened for germline transmission. Gene loc... NXR
Xla.sox10emHorb

X.laevis sox10.L CRISPR knockout of sox10 (SRY-box 10). Confirmed germline transmission. Mutant line generated by Hor... NXR
Xla.slc16a2emHorb

X.laevis slc16a2.L CRISPR knockout of slc16a2 (solute carrier family 16, member 2 (thyroid hormone transporter)). Curre... NXR
Xla.mitfemHorb

X.laevis mitf.L CRISPR knockout of mitf (melanocyte inducing transcription factor) Currently mosaic founders. Not sc... NXR
Xla.prph2emHorb

X.laevis prph2.L CRISPR knockout of prph2 (peripherin 2 (retinal degeneration, slow)). Current mosaic founders, not t... NXR
Xla.gfi1emHorb

X.laevis gfi1.L CRISPR knockout of gfi1 (growth factor independent 1 transcription repressor ).Confirmed germline tr... NXR
Xla.prickle1emHorb

X.laevis prickle1.L CRISPR knockout of prickle1(prickle planar cell polarity protein 1). Confirmed germline transmission... NXR
Xla.fxr1emHorb

X.laevis fxr1.L CRISPR Knockout of fxr1(FMR1 autosomal homolog 1 ). Currently mosaic founders. Confirmed germline tr... NXR
Xla.eya1emHorb

X.laevis eya1.L CRISPR Knockout of eya1. Currently mosaic founders. not screened for germline transmission. Mutant l... NXR
Xla.ppp2r2aemHorb

X.laevis ppp2r2a.L CRISPR knockout of ppp2r2a (protein phosphatase 2 regulatory subunit B, alpha ). Current mosaic foun... NXR

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