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Results 1 - 50 of 64 results

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Line Name Species Mutated Gene Description Availability
Xtr.rflciiemNXR

X.tropicalis rflcii CRISPR KO of rflcii ( relaxin family locus C type II ) in X tropicalis. Germ line transmission not y... NXR
Xtr.nr2f2emNXR

X.tropicalis nr2f2 CRISPR knockout fo nr2f2 (nuclear receptor subfamily 2 group F member 2 ). Germ line transmission co... NXR
Xtr.myf6emNXR

X.tropicalis myf6 TALENS knockout of myf6 (myogenic factor 6) in X tropicalis. Germ line transmission not yet confirme... NXR
Xtr.kiff11emHorb

X.tropicalis kif11 CRISPR knockout of kif11 (kinesin family member 11). Germ line transmission not yet confirmed. F0 fo... NXR
Xtr.gfi1em2Horb

X.tropicalis gfi1 CRISPR knockout of gfi1 (growth factor independent 1 transcription repressor). Germ line transmissio... NXR
Xtr.eya1em1NXR

X.tropicalis eya1 CRISPR knockout of eya1 (EYA transcriptional coactivator and phosphatase 1). Germline transmission ... NXR
Xla.xdm-wemNXR

X.laevis xdm-w.L CRISPR knock out of xdm-w (doublesex and mab3 related transcription factor W ). Germ Line transmissi... NXR
Xla.dmrt1em3NXR

X.laevis dmrt1.S CRISPR knockout of dmrt1.S (doublesex and mab-3 related transcription factor 1 ). Custom mutant line... NXR
Xla.dmrt1em1NXR

X.laevis dmrt1.L CRISPR knockout of dmrt1.L (doublesex and mab-3 related transcription factor 1 ). Germ line transmis... NXR
Xtr.csnk1g2emNXR

X.tropicalis csnk1g2 CRISPR knockout of csnk1g2 (casein kinase 1 gamma 2). Germ line transmission confirmed. Mutation is ... NXR
Xla.ccdc78emNXR

X.laevis ccdc78.S CRISPR knockout of ccdc78 (coiled-coil domain containing 78). Germ line transmission confirmed. Muta... NXR
Xtr.cacna1hem1NXR

X.tropicalis cacna1h CRISPR knockout of cacna1h (calcium channel, voltage-dependent, T type, alpha 1H subunit). Mutation ... NXR
Xla.ar em1NXR

X.laevis ar.L CRISPR mutation of ar (androgen receptor). Mutation is confirmed as a 13bp deletion in ar.L. germlin... NXR
Xtr.amhr2emNXR

X.tropicalis amhr2 CRISPR knockout of amhr2 (anti-Mullerian hormone receptor type II ). Confirmed germline transmission... NXR
Xtr.amhem3NXR

X.tropicalis amh CRISPR knockout of amh (anti-Mullerian hormone ). Confirmed germline transmission. Custom mutant gen... NXR
Xtr.ahrem1NXR

X.tropicalis ahr TALEN generated mutant line, made by the NXR. Germ line transmission confirmed. ,+2bp mutation: CCAT... NXR
Xla.adam33emNXR

X.laevis adam33.L CRISPR knockout of adam33 (ADAM metallopeptidase domain 33 ). Confirmed germline transmission. Custo... NXR
Xla.Tg(kcp)tmConlon

X.laevis kcp.L One-cell stage Xenopus Xla.Tg(Cardiac-actin:GFP)Mohun embryos were microinjected with 1 ng TALEN mRN...
Xtr.tp53em_del1/em_del2_Vlemx

X.tropicalis tp53 Two types of F1 tp53 heterozygotes, each with a distinct variant of a deletion (em_del1/+ and em_del...
Xla.hps4m

X.laevis hps4.L This periodic albino mutant of Xenopus laevis is a recessive mutant. Fukazawa et al 2020 showed that...
Xtr.tp53em_del2/+_Vlemx

X.tropicalis tp53 Deletion is expected to give rise to nonsense-mediated decay since due to the frame-shifting deletio...
Xtr.tp53em_del1/+_Vlemx

X.tropicalis tp53 Deletion is expected to give rise to nonsense-mediated decay since due to the frame-shifting deleti...
Xtr.tbxt,tbxt.2emJcsm

X.tropicalis tbxt Double talen-induced mutant line. Talen induced 2-bp deletion in exon 1 of tbxt and 7 bp deletion in... EXRC
Xtr.tbxt.2em2Jcsm

X.tropicalis tbxt.2 Talen-induced mutant line. Talen-induced 7-bp deletion in third exon of T, brachyury homolog, gene ... EXRC
Xtr.tbxt.2em1Jcsm

X.tropicalis tbxt.2 Talen-mediated mutant line. Talen-induced 7-bp deletion in third exon of T, brachyury homolog, gene ... EXRC
Xla.npffr1.1emEXRC

X.laevis npffr1.1.L Crispr-Cas9 mutation in the npffr1.1 gene (neuropeptide FF receptor 1, gene 1 ). EXRC
Xtr.tbxtemJcsm

X.tropicalis tbxt Talen-induced 2bp deletion in exon 1 of tbxt (T-box transcription factor T) gene. Mutation destroys ... EXRC
Xtr.smad4.1mZimml

X.tropicalis smad4 Mutation affecting haematopoiesis identified in a screen for ENU-induced mutations at Mill Hill. Pos... EXRC
Xtr.dstmZimml

X.tropicalis unknown Mutation affecting the haematopoietic system identified in the Mill Hill screen for ENU-induced muta... EXRC
Xtr.tupmZimml

X.tropicalis unknown Mutation affecting axial development identified in the Mill Hill screen of ENU-induced mutations. EXRC
Xtr.legmZimml

X.tropicalis unknown Mutation affecting otoconia formation identified in the Mill Hill screen of ENU-induced mutations. EXRC
Xtr.amhem1NXR

X.tropicalis amh CRISPR knockout of amh (anti-Mullerian hormone). Germline transmission confirmed. +8bp mutation in a... NXR
Xtr.gfi1em1Horb

X.tropicalis gfi1 CRISPR knockout of gfi1 (growth factor independent 1 transcription repressor). Germ line transmissio... NXR
Xtr.wt1emHorb

X.tropicalis wt1 CRISPR knockout of wt1 (Wilms tumor 1). Not screened for germline transmission. NXR
Xla.pkhd1emHorb

X.laevis pkhd1.L CRISPR knockout of pkhd1 (PKHD1, fibrocystin/polyductin), Germ line transmission confirmed. Animals ... NXR
Xtr.dtlemHorb

X.tropicalis dtl CRISPR knockout of dtl (denticleless E3 ubiquitin protein ligase homolog), Current mosaic founders, ... NXR
Xtr.shroom3emHorb

X.tropicalis shroom3 CRISPR knockout of shroom3 (shroom family member 3), Current mosaic founders, Not tested for germlin... NXR
Xtr.zbtb21emHorb

X.tropicalis zbtb21 CRISPR knockout of zbtb21(zinc finger and BTB domain containing 21), Current mosaic founders, Not te... NXR
Xtr.tspan8emHorb

X.tropicalis tspan8 CRISPR knockout of tspan8 (tetraspanin 8), Current mosaic founders, Not tested for germline transmis... NXR
Xtr.sox3emHorb

X.tropicalis sox3 CRISPR knockout of sox3 (SRY-box 3), Current mosaic founders, Not tested for germline transmission. ... NXR
Xtr.ezh2emHorb

X.tropicalis ezh2 CRISPR knockout of ezh2 (enhancer of zeste 2 polycomb repressive complex 2 subunit), Germ line trans... NXR
Xtr.tbx2emHorb

X.tropicalis tbx2 CRISPR knockout of tbx2 (T-box 2), Current mosaic founders, Not tested for germline transmission. NXR
Xtr.zbtb14emHorb

X.tropicalis zbtb14 CRISPR knockout of zbtb14 (zinc finger and BTB domain containing 14). Germ line transmission not yet... NXR
Xtr.tlx3em2Horb

X.tropicalis tlx3 2nd CRISPR mutant line targeting tlx3 (T cell leukemia homeobox 3). Germ lIne transmission confirmed... NXR
Xtr.fibinemHorb

X.tropicalis fibin CRISPR knockout of fibin (fin bud initiation factor homolog), Confirmed germline transmission. Custo... NXR
Xtr.tbx5emHorb

X.tropicalis tbx5 CRISPR knockout of tbx5 (T-box 5 ), Confirmed germline transmission. Custom mutant generated by Horb... NXR
Xtr.tyremNXR

X.tropicalis tyr CRISPR knockout of tyr (tyrosinase), Confirmed germline transmission. Custom mutant generated by the... NXR
Xtr.raxmGrngr

X.tropicalis rax This mutant line was generated in an ENU screen from the Grainger lab by TILLING (Targeting Induced ... NXR
Xla.wnt11emHorb

X.laevis wnt11.L CRISPR knockout of wnt11 (Wnt family member 11 ), Confirmed germline transmission. Mutant line gener... NXR
Xla.wdpcpemHorb

X.laevis wdpcp.L CRISPR knockout of wdpcp (WD repeat containing planar cell polarity effector). Current mosaic founde... NXR

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