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Results 1 - 50 of 98 results

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Line Name Species Mutated Gene Description Availability
Xtr.zbtb21emHorb

X.tropicalis zbtb21 CRISPR knockout of zbtb21(zinc finger and BTB domain containing 21), Current mosaic founders, Not te... NXR
Xtr.zbtb14emHorb

X.tropicalis zbtb14 CRISPR knockout of zbtb14 (zinc finger and BTB domain containing 14). Germ line transmission not yet... NXR
Xtr.wwoxemHorb

X.tropicalis wwox CRISPR knockout of wwox (WW domain containing oxidoreductase). Not screened for germline transmissio... NXR
Xtr.wt1emHorb

X.tropicalis wt1 CRISPR knockout of wt1 (Wilms tumor 1). Not screened for germline transmission. NXR
Xtr.unc45bmZimml

X.tropicalis unc45b Mutation affecting striated muscle identified in the Mill Hill screen for ENU-induced mutations. EXRC
Xtr.tyremNXR

X.tropicalis tyr CRISPR knockout of tyr (tyrosinase), Confirmed germline transmission. Custom mutant generated by the... NXR
Xtr.tupmZimml

X.tropicalis unknown Mutation affecting axial development identified in the Mill Hill screen of ENU-induced mutations. EXRC
Xtr.tspan8emHorb

X.tropicalis tspan8 CRISPR knockout of tspan8 (tetraspanin 8), Current mosaic founders, Not tested for germline transmis... NXR
Xtr.tlx3em2Horb

X.tropicalis tlx3 2nd CRISPR mutant line targeting tlx3 (T cell leukemia homeobox 3). Germ lIne transmission confirmed... NXR
Xtr.tlx3em1Horb

X.tropicalis tlx3 CRISPR knockout of tlx3 (T cell leukemia homeobox 3). Confirmed germline transmission. Custom mutant... NXR
Xtr.tbxtemJcsm

X.tropicalis tbxt Talen-induced 2bp deletion in exon 1 of tbxt (T-box transcription factor T) gene. Mutation destroys ... EXRC
Xtr.tbxt.2em2Jcsm

X.tropicalis tbxt.2 Talen-induced mutant line. Talen-induced 7-bp deletion in third exon of T, brachyury homolog, gene ... EXRC
Xtr.tbxt.2em1Jcsm

X.tropicalis tbxt.2 Talen-mediated mutant line. Talen-induced 7-bp deletion in third exon of T, brachyury homolog, gene ... EXRC
Xtr.tbxt,tbxt.2emJcsm

X.tropicalis tbxt Double talen-induced mutant line. Talen induced 2-bp deletion in exon 1 of tbxt and 7 bp deletion in... EXRC
Xtr.tbx5emHorb

X.tropicalis tbx5 CRISPR knockout of tbx5 (T-box 5 ), Confirmed germline transmission. Custom mutant generated by Horb... NXR
Xtr.tbx2emHorb

X.tropicalis tbx2 CRISPR knockout of tbx2 (T-box 2), Current mosaic founders, Not tested for germline transmission. NXR
Xtr.supt5hmZimml

X.tropicalis supt5h Mutation affecting eye development and melanophore migration identified in the Mill Hill screen for ... EXRC
Xtr.sox3emHorb

X.tropicalis sox3 CRISPR knockout of sox3 (SRY-box 3), Current mosaic founders, Not tested for germline transmission. ... NXR
Xtr.sox2emHorb

X.tropicalis sox2 CRISPR knockout of sox2 (SRY-box 2). Not screened for germline transmission. NXR
Xtr.smad4.1mZimml

X.tropicalis smad4.1 Mutation affecting haematopoiesis identified in a screen for ENU-induced mutations at Mill Hill. Pos... EXRC
Xtr.shroom3emHorb

X.tropicalis shroom3 CRISPR knockout of shroom3 (shroom family member 3), Current mosaic founders, Not tested for germlin... NXR
Xtr.rxrgemHorb

X.tropicalis rxrg Description: CRISPR knockout of rxrg (retinoid X receptor gamma). Confirmed germline transmission. C... NXR
Xtr.rxrbemHorb

X.tropicalis rxrb CRISPR knockout of rxrb (retinoid X receptor beta). Confirmed germline transmission. Custom mutant g... NXR
Xtr.runx2emHorb

X.tropicalis runx2 CRISPR knockout of runx2 (runt related transcription factor 2). This mutation is lethal during metam... NXR
Xtr.runx1emHorb

X.tropicalis runx1 CRISPR knockout of runx1(runt related transcription factor 1). Current mosaic founders, not tested f... NXR
Xtr.runx1t1emHorb

X.tropicalis runx1t1 CRISPR knockout of runx1t1( RUNX1 translocation partner 1) gene. Germ line transmission not yet conf... NXR
Xtr.raxtmGrngr

X.tropicalis rax This mutant line was generated in an ENU screen from the Grainger lab by TILLING (Targeting Induced ... NXR
Xtr.prph2emHorb

X.tropicalis prph2 CRISPR knockout of prph2 (peripherin 2 (retinal degeneration, slow)). Confirmed germline transmissio... NXR
Xtr.pou3f4emHorb

X.tropicalis pou3f4 CRISPR knockout of pou3f4 (POU class 3 homeobox 4). Current mosaic founders, not tested for germline... NXR
Xtr.petmZimml

X.tropicalis unknown Homozygous mutants are completely paralyzed with no heartbeat. EXRC
Xtr.otx2emHorb

X.tropicalis otx2 CRISPR knockout of otx2 (orthodenticle homeobox 2). Not screened for germline transmission. NXR
Xtr.olig4emHorb

X.tropicalis olig4 CRISPR knockout of olig4 (oligodendrocyte transcription factor 4). Current mosaic founders, not test... NXR
Xtr.olig2emHorb

X.tropicalis olig2 CRISPR knockout of olig2 (oligodendrocyte lineage transcription factor 2). Confirmed germline transm... NXR
Xtr.oc90mZimml

X.tropicalis oc90 Mutation affecting inner ear otoconia identified in the Mill Hill screen for ENU-induced mutations. ... EXRC
Xtr.npntinsZimml

X.tropicalis npnt Nephronectin insertional mutation (probably null). Insertion of Tg(nkx2.5:GFP) transgene between 3rd... EXRC
Xtr.notch4emHorb

X.tropicalis notch4 CRISPR knockout of notch4. Confirmed germline transmission. NXR
Xtr.nhlh1emHorb

X.tropicalis nhlh1 CRISPR knockout of nhlh1 (nescient helix-loop-helix 1). Not screened for germline transmission. NXR
Xtr.myt1emHorb

X.tropicalis myt1 CRISPR knockout of myt1 (myelin transcription factor 1). Not tested for germline transmission. NXR
Xtr.myh6mZimml

X.tropicalis myh6 Mutation affecting cardiac function identified in the Mill Hill screen of ENU-induced mutations. Non... EXRC
Xtr.mlomZimml

X.tropicalis unknown Mutation affecting striated muscle identified in the Mill Hill screen for ENU-induced mutations. Map... EXRC
Xtr.mitfemHorb

X.tropicalis mitf CRISPR knockout of mitf (melanocyte inducing transcription factor). Current mosaic founders, not tes... NXR
Xtr.map3k13emHorb

X.tropicalis map3k13 CRISPR knockout of map3k13 (mitogen-activated protein kinase kinase kinase 13). Confirmed germline t... NXR
Xtr.mammZimml

X.tropicalis unknown Mutation affecting cardiac function identified in a screen for ENU-induced mutations at Mill Hill EXRC
Xtr.lmnaemHorb

X.tropicalis lmna CRISPR knockout of lmna (lamin A/C).Confirmed germline transmission. Custom mutant generated by Horb... NXR
Xtr.legmZimml

X.tropicalis unknown Mutation affecting otoconia formation identified in the Mill Hill screen of ENU-induced mutations. EXRC
Xtr.kng1emHorb

X.tropicalis kng1 CRISPR knockout of kng1(kininogen 1), Current mosaic founders, Not tested for germline transmission.... NXR
Xtr.kcnj8emHorb

X.tropicalis kcnj8 CRISPR knockout of kcnj8 (potassium channel, inwardly rectifying subfamily J, member 8). Not screene... NXR
Xtr.junbemHorb

X.tropicalis junb CRISPR knockout of junb (jun B proto-oncogene), Current mosaic founders, Not tested for germline tra... NXR
Xtr.insm2emHorb

X.tropicalis insm2 CRISPR knockout of insm2 (insulinoma-associated 2). Confirmed germline transmission. Custom mutant g... NXR
Xtr.hpse2emHorb

X.tropicalis hpse2 CRISPR knockout of hpse2 (heparanase 2 (inactive)). Confirmed germline transmission. Custom mutant g... NXR

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