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Results 1 - 50 of 210 results

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Line Name Species Mutated Gene Description Availability
Xtr.zmym4emNXR

X.tropicalis zmym4 CRISPR KO of zmym4 (zinc finger MYM-type containing 4) in X. tropicalis. Currently mosaic founds F0 ... NXR
Xtr.zeb2emNXR

X.tropicalis zeb2 CRISPR KO of zeb2 (zinc finger E-box binding homeobox 2), a gene associated with Mowat-Wilson syndro... NXR
Xtr.zbtb21emHorb

X.tropicalis zbtb21 CRISPR knockout of zbtb21(zinc finger and BTB domain containing 21), Current mosaic founders, Not te... NXR
Xtr.zbtb14emHorb

X.tropicalis zbtb14 CRISPR knockout of zbtb14 (zinc finger and BTB domain containing 14). Germ line transmission confirm... NXR
Xtr.ywhazemNXR

X.tropicalis ywhaz CRISPR KO of ywhaz (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta). ge...
Xtr.xbp1emNXR

X.tropicalis xbp1 CRISPR KO of xbp1 ( X-box binding protein 1 ) a gene assocaited with Major Affected Disorder in huma... NXR
Xtr.wwoxemHorb

X.tropicalis wwox CRISPR knockout of wwox (WW domain containing oxidoreductase), a gene associated with esophageal can... NXR
Xtr.wt1emHorb

X.tropicalis wt1 CRISPR knockout of wt1 (Wilms tumor 1). Germ line transmission confirmed. Animals carry a 5bp deleti... NXR
Xtr.wnt11bemNXR

X.tropicalis wnt11b CRISPR knockout of wnt11b (wingless-type MMTV integration site family, member 11B ), Germ line tran... NXR
Xtr.wbp11emNXR

X.tropicalis wbp11 CRISPR knockout of wbp11 (WW domain binding protein 11). Germline transmission confirmed, F2s growin... NXR
Xtr.vwa2emNXR

X.tropicalis vwa2 CRISPR knock out of vwa2 (von Willebrand factor A domain containing 2 ). Germ line transmission conf... NXR
Xtr.vangl2emNXR

X.tropicalis vangl2 CRISPR knockout of vangl2 (VANGL planar cell polarity protein 2 ), a gene associated with neural tub... NXR
Xtr.unc45bmZimml

X.tropicalis unc45b Mutation affecting striated muscle identified in the Mill Hill screen for ENU-induced mutations. EXRC
Xtr.tyremNXR

X.tropicalis tyr CRISPR knockout of tyr (tyrosinase), Confirmed germline transmission. Animal carry a 241bp insertion... NXR
Xtr.tupmZimml

X.tropicalis unknown Mutation affecting axial development identified in the Mill Hill screen of ENU-induced mutations. EXRC
Xtr.tspan8em3Horb

X.tropicalis tspan8 CRISPR knockout of tspan8 (tetraspanin 8), Germ line transmission confirmed. 3rd of 3 tspan lines at...
Xtr.tspan8em2Horb

X.tropicalis tspan8 CRISPR knockout of tspan8 (tetraspanin 8), Germ line transmission confirmed. 2nd of 3 tspan lines at... NXR
Xtr.tspan8em1Horb

X.tropicalis tspan8 CRISPR knockout of tspan8 (tetraspanin 8), Germ line transmission confirmed. 1of 3 tspan lines at th... NXR
Xtr.tp53em_del2/+_Vlemx

X.tropicalis tp53 Deletion is expected to give rise to nonsense-mediated decay since due to the frame-shifting deletio...
Xtr.tp53em_del1/+_Vlemx

X.tropicalis tp53 Deletion is expected to give rise to nonsense-mediated decay since due to the frame-shifting deleti...
Xtr.tlx3em2Horb

X.tropicalis tlx3 CRISPR mutant line targeting tlx3 (T cell leukemia homeobox 3). Germ lIne transmission was confirmed...
Xtr.tlx3em1Horb

X.tropicalis tlx3 CRISPR knockout of tlx3 (T cell leukemia homeobox 3). Confirmed germline transmission. Custom mutant... NXR
Xtr.thratmShiyb

X.tropicalis This line was created using TALENS targeting exon 4 (the third coding exon) of the X. tropicalis thr...
Xtr.tdrd1emNXR

X.tropicalis tdrd1 CRISPR knockout of tdrd1 (tudor domain containing 1). Germline transmission not yet confirmed. growi... NXR
Xtr.tbxtemJcsm

X.tropicalis tbxt Talen-induced 2bp deletion in exon 1 of tbxt (T-box transcription factor T) gene. Mutation destroys ... EXRC
Xtr.tbxt.2em2Jcsm

X.tropicalis tbxt.2 Talen-induced mutant line. Talen-induced 7-bp deletion in third exon of T, brachyury homolog, gene ... EXRC
Xtr.tbxt.2em1Jcsm

X.tropicalis tbxt.2 Talen-mediated mutant line. Talen-induced 7-bp deletion in third exon of T, brachyury homolog, gene ... EXRC
Xtr.tbxt,tbxt.2emJcsm

X.tropicalis tbxt Double talen-induced mutant line. Talen induced 2-bp deletion in exon 1 of tbxt and 7 bp deletion in... EXRC
Xtr.tbx5emHorb

X.tropicalis tbx5 CRISPR knockout of tbx5 (T-box 5 ), Confirmed germline transmission. Custom mutant generated by Horb... NXR
Xtr.tbx2emHorb

X.tropicalis tbx2 CRISPR knockout of tbx2 (T-box 2), Current mosaic founders, Not tested for germline transmission. NXR
Xtr.supt5hmZimml

X.tropicalis supt5h Mutation affecting eye development and melanophore migration identified in the Mill Hill screen for ... EXRC
Xtr.srd5a3emNXR

X.tropicalis srd5a3 CRISPR knockout of srd5a3 (steroid 5 alpha-reductase 3), Germ line transmission not yet confirmed. C... NXR
Xtr.srd5a2emNXR

X.tropicalis srd5a2 CRISPR knockout of srd5a2 (steroid 5 alpha-reductase 2), Confirmed germ line transmission. animals c... NXR
Xtr.sox3emHorb

X.tropicalis sox3 CRISPR knockout of sox3 (SRY-box 3), Current mosaic founders, Not tested for germline transmission. ... NXR
Xtr.sox2emHorb

X.tropicalis sox2 CRISPR knockout of sox2 (SRY-box 2). Germ line transmission confirmed. Animals carry a 1bp insertion... NXR
Xtr.snai2emNXR

X.tropicalis snai2 CRISPR knockout of snai2 (snail family zinc finger 2) in X. tropicalis. Germ line transmission confi... NXR
Xtr.snai1emNXR

X.tropicalis snai1 CRISPR knockout of snai1 (snail family zinc finger 1) in X. tropicalis. germline transmission confir... NXR
Xtr.smad4.1mZimml

X.tropicalis smad4 Mutation affecting haematopoiesis identified in a screen for ENU-induced mutations at Mill Hill. Pos... EXRC
Xtr.six1em2NXR

X.tropicalis six1 CRISPR knockout of six1 (SIX homeobox 1), a gene associated with branchiootorenal syndrome and branc... NXR
Xtr.six1em1NXR

X.tropicalis six1 CRISPR knockout of six1 (SIX homeobox 1), a gene associated with branchiootorenal syndrome and branc... NXR
Xtr.shroom3emHorb

X.tropicalis shroom3 CRISPR knockout of shroom3 (shroom family member 3), Current mosaic founders, Germ line transmissio... NXR
Xtr.sf3b4emNXR

X.tropicalis sf3b4 CRISPR knockout of sf3b4 (splicing factor 3b subunit 4) in X tropicalis. sf3b4 is a gene associated ... NXR
Xtr.rxrgemHorb

X.tropicalis rxrg Description: CRISPR knockout of rxrg (retinoid X receptor gamma). Confirmed germline transmission. C... NXR
Xtr.rxrbemHorb

X.tropicalis rxrb CRISPR knockout of rxrb (retinoid X receptor beta). Confirmed germline transmission. Animals carry a... NXR
Xtr.rxraemNXR

X.tropicalis rxra CRISPR knockout of rxra (retinoid X receptor alpha ). Germ line transmission confirmed. Contact NXR... NXR
Xtr.runx2emHorb

X.tropicalis runx2 CRISPR knockout of runx2 (runt related transcription factor 2). Contact NXR to inquire about availab... NXR
Xtr.runx1em3NXR

X.tropicalis runx1 CRISPR knockout of runx1(runt related transcription factor 1). Germ line transmission confirmed. Ani... NXR
Xtr.runx1em2NXR

X.tropicalis runx1 CRISPR knockout of runx1(runt related transcription factor 1). Germ line transmission confirmed. Ani... NXR
Xtr.runx1em1Horb

X.tropicalis runx1 CRISPR knockout of runx1(runt related transcription factor 1). Germ line transmission confirmed. Ani... NXR
Xtr.runx1t1emHorb

X.tropicalis runx1t1 CRISPR knockout of runx1t1( RUNX1 translocation partner 1) gene. Germ line transmission not yet conf... NXR

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