XB-LINE-1260
Line Name: Xla.pkd2emHorb
| Summary |
|
| Synonym: |
Xla.pkd2tmHorb |
| Species: |
Xenopus laevis |
| Background Strain: |
Xla.Inbred
|
| Paternal Line: |
Xla.J-strainNXR |
| Maternal Line: |
Xla.J-strainNXR |
| Description: |
CRISPR knockout of pkd2 (polycystin 2, transient receptor potential cation channel ). Germ line transmission confirmed. Animals carry a 16 base pair deletion or a 20 base pair deletion in pkd2.L. |
| Phenotype Description: |
-16 base pair mutation sequence GCGTGGGAGC----------------CACACGGAAC and -20 base pair mutation sequence GTCTGTACTG--------------------GGACAATGGC. Associated with human autosomal dominant polycystic kidney disease. |
| Color Morph: |
pigmented |
| Breeding Type: |
OUTBRED
|
| Lab of Origin: |
Horb Lab |
| Line Type: |
Mutant |
| Mutated Gene(s): |
pkd2.L
|
| MTA Required: |
No
|
| Public: |
Yes
|
| Catalog Number: |
NXR_2010 |
| Stock Center |
RRID |
Generation |
DOB |
# Males |
# Females |
Availability |
Mutant Details |
| NXR (US) |
NXR_2010 |
F2+ |
|
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