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Summary Attributions Transgene
XB-LINE-997

Line Name: Xtr.Tg(WntREs:dEGFP;CMV:dsRed)Vlemx


Summary
Synonym: pbin7Lef:dGFP F2, pbin7Lef:dGFP-H (F2)
Species: Xenopus tropicalis
Background Strain: Xtr.Outbred
Paternal Line:
Maternal Line:
Description: The inserted transgene construct contains a synthetic Wnt-responsive promoter consisting of 7 copies of a TCF/LEF1 binding DNA element, a minimal TATA box and a reporter gene encoding destabilized EGFP and a polyA sequence. The transgene is flanked on both sides by two copies of the chicken HS4-core sequence. See Tran et al., 2010 and 2013 for a full description. Likely due to a (unknown) transgene integration event, the animals can produce pseudo-albino (no red eyes) off-spring.
Phenotype Description: GFP expression reveals dynamic patterns of Wnt/beta-catenin signaling activity First clear signals present at neurula stage (NF stage 19) in the neural folds.
Color Morph: albino
Breeding Type: UNKNOWN
Lab of Origin:
Line Type: Transgenic
Mutated Gene(s):
MTA Required: No
Public: Yes
Catalogue Number:

Stock Center RRID Generation Availability Mutant Details
NXR (US)
EXRC (Europe)
NBRP (Japan)
XLRRI (US)

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