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Summary Attributions
XB-TRANSGENE-18006069
Transgene Name Tg(atp6v0cdel)
Description atp6v03 (Ductin) construct lacking the 4th transmembrane domain; inhibits H+-V-ATPase, which has structural as well as ion-transporter function. This truncated ductin mutant entirely eliminates the proton binding site. Also known as atp6v0c-noTM4. Reference: Nishi T, Forgac M. 2002. The vacuolar H+-ATPASES: nature's most versatile proton pumps. Nat Rev Mol Cell Biol 3: 94-103.
Inducibility None

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