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XB-TRANSGENE-18006069
Transgene Name | Tg(atp6v0cdel) |
Description | atp6v03 (Ductin) construct lacking the 4th transmembrane domain; inhibits H+-V-ATPase, which has structural as well as ion-transporter function. This truncated ductin mutant entirely eliminates the proton binding site. Also known as atp6v0c-noTM4. Reference: Nishi T, Forgac M. 2002. The vacuolar H+-ATPASES: nature's most versatile proton pumps. Nat Rev Mol Cell Biol 3: 94-103. |
Inducibility | None |
Components |
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