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Membrane potential drives the exit from pluripotency and cell fate commitment via calcium and mTOR. , Sempou E., Nat Commun. November 5, 2022; 13 (1): 6681.
Mutations in the voltage-gated potassium channel gene KCNH1 cause Temple-Baraitser syndrome and epilepsy. , Simons C., Nat Genet. January 1, 2015; 47 (1): 73-7.
Marine algal toxin azaspiracid is an open-state blocker of hERG potassium channels. , Twiner MJ., Chem Res Toxicol. September 17, 2012; 25 (9): 1975-84.
Effects of the histamine H(1) receptor antagonist hydroxyzine on hERG K(+) channels and cardiac action potential duration. , Lee BH., Acta Pharmacol Sin. September 1, 2011; 32 (9): 1128-37.
Block of the human ether-a- go-go-related gene ( hERG) K+ channel by the antidepressant desipramine. , Hong HK., Biochem Biophys Res Commun. April 9, 2010; 394 (3): 536-41.
Block effect of capsaicin on hERG potassium currents is enhanced by S6 mutation at Y652. , Xing J., Eur J Pharmacol. March 25, 2010; 630 (1-3): 1-9.
Block of HERG k channel by classic histamine h(1) receptor antagonist chlorpheniramine. , Hong HK., Korean J Physiol Pharmacol. June 1, 2009; 13 (3): 215-20.
Probing the binding sites and mechanisms of action of two human ether-a- go-go-related gene channel activators, 1,3- bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643) and 2-[2-(3,4-dichloro-phenyl)-2,3-dihydro-1H-isoindol-5-ylamino]-nicotinic acid (PD307243). , Xu X., Mol Pharmacol. June 1, 2008; 73 (6): 1709-21.
Effect of S5P alpha-helix charge mutants on inactivation of hERG K+ channels. , Clarke CE., J Physiol. June 1, 2006; 573 (Pt 2): 291-304.
Blockade of HERG human K+ channels and IKr of guinea-pig cardiomyocytes by the antipsychotic drug clozapine. , Lee SY., Br J Pharmacol. June 1, 2006; 148 (4): 499-509.
Inhibition of human ether-a- go-go-related gene K+ channel and IKr of guinea pig cardiomyocytes by antipsychotic drug trifluoperazine. , Choi SY., J Pharmacol Exp Ther. May 1, 2005; 313 (2): 888-95.
Block of wild-type and inactivation-deficient human ether-a- go-go-related gene K+ channels by halofantrine. , Sánchez-Chapula JA., Naunyn Schmiedebergs Arch Pharmacol. December 1, 2004; 370 (6): 484-91.
Gating charges in the activation and inactivation processes of the HERG channel. , Zhang M., J Gen Physiol. December 1, 2004; 124 (6): 703-18.
Inhibition of human ether-a- go-go-related gene potassium channels by alpha 1-adrenoceptor antagonists prazosin, doxazosin, and terazosin. , Thomas D., Naunyn Schmiedebergs Arch Pharmacol. May 1, 2004; 369 (5): 462-72.
Voltage-dependent profile of human ether-a- go-go-related gene channel block is influenced by a single residue in the S6 transmembrane domain. , Sănchez-Chapula JA., Mol Pharmacol. May 1, 2003; 63 (5): 1051-8.
Molecular determinants of voltage-dependent human ether-a- go-go related gene ( HERG) K+ channel block. , Sánchez-Chapula JA., J Biol Chem. June 28, 2002; 277 (26): 23587-95.
Molecular determinants of inactivation and dofetilide block in ether a- go-go ( EAG) channels and EAG-related K(+) channels. , Ficker E., Mol Pharmacol. December 1, 2001; 60 (6): 1343-8.
High-affinity blockade of human ether-a- go-go-related gene human cardiac potassium channels by the novel antiarrhythmic drug BRL-32872. , Thomas D., J Pharmacol Exp Ther. May 1, 2001; 297 (2): 753-61.
Blockade of the HERG human cardiac K(+) channel by the antidepressant drug amitriptyline. , Jo SH., Br J Pharmacol. April 1, 2000; 129 (7): 1474-80.
Molecular determinants for activation and inactivation of HERG, a human inward rectifier potassium channel. , Schönherr R., J Physiol. June 15, 1996; 493 ( Pt 3) 635-42.