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Extracellular cysteine disulfide bond break at Cys122 disrupts PIP 2 -dependent Kir2.1 channel function and leads to arrhythmias in Andersen-Tawil Syndrome. , Cruz FM., bioRxiv. June 8, 2023;
Class III antiarrhythmic drug dronedarone inhibits cardiac inwardly rectifying Kir2.1 channels through binding at residue E224. , Xynogalos P., Naunyn Schmiedebergs Arch Pharmacol. December 1, 2014; 387 (12): 1153-61.
Up-regulation of Kir2.1 ( KCNJ2) by the serum & glucocorticoid inducible SGK3. , Munoz C., Cell Physiol Biochem. January 1, 2014; 33 (2): 491-500.
Inhibition of Kir2.1 ( KCNJ2) by the AMP-activated protein kinase. , Alesutan I., Biochem Biophys Res Commun. May 20, 2011; 408 (4): 505-10.
Kir2.x inward rectifier potassium channels are differentially regulated by adrenergic alpha1A receptors. , Zitron E., J Mol Cell Cardiol. January 1, 2008; 44 (1): 84-94.
Differential effects of volatile and intravenous anesthetics on the activity of human TASK-1. , Putzke C., Am J Physiol Cell Physiol. October 1, 2007; 293 (4): C1319-26.
Kir2.3 isoform confers pH sensitivity to heteromeric Kir2.1/ Kir2.3 channels in HEK293 cells. , Muñoz V., Heart Rhythm. April 1, 2007; 4 (4): 487-96.
Functional and clinical characterization of KCNJ2 mutations associated with LQT7 (Andersen syndrome). , Tristani-Firouzi M., J Clin Invest. August 1, 2002; 110 (3): 381-8.
Unitary conductance variation in Kir2.1 and in cardiac inward rectifier potassium channels. , Picones A., Biophys J. October 1, 2001; 81 (4): 2035-49.
Direct block of inward rectifier potassium channels by nicotine. , Wang H., Toxicol Appl Pharmacol. April 1, 2000; 164 (1): 97-101.
The role of Kir2.1 in the genesis of native cardiac inward-rectifier K+ currents during pre- and postnatal development. , Nakamura TY., Ann N Y Acad Sci. April 30, 1999; 868 434-7.
Kir2.1 encodes the inward rectifier potassium channel in rat arterial smooth muscle cells. , Bradley KK., J Physiol. March 15, 1999; 515 ( Pt 3) 639-51.
Inhibition of rat ventricular IK1 with antisense oligonucleotides targeted to Kir2.1 mRNA. , Nakamura TY., Am J Physiol. March 1, 1998; 274 (3): H892-900.
Cloning and functional expression of an inwardly rectifying K+ channel from human atrium. , Wible BA., Circ Res. March 1, 1995; 76 (3): 343-50.