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Structural and electrophysiological basis for the modulation of KCNQ1 channel currents by ML277. , Willegems K., Nat Commun. June 29, 2022; 13 (1): 3760.
Modulating the voltage sensor of a cardiac potassium channel shows antiarrhythmic effects. , Lin Y., Proc Natl Acad Sci U S A. May 18, 2021; 118 (20):
In vitro and in vivo characterization of Lu AA41178: A novel, brain penetrant, pan-selective Kv7 potassium channel opener with efficacy in preclinical models of epileptic seizures and psychiatric disorders. , Grupe M., Eur J Pharmacol. November 15, 2020; 887 173440.
Bioelectric signalling via potassium channels: a mechanism for craniofacial dysmorphogenesis in KCNJ2-associated Andersen-Tawil Syndrome. , Adams DS ., J Physiol. June 15, 2016; 594 (12): 3245-70.
AMP-activated protein kinase in BK-channel regulation and protection against hearing loss following acoustic overstimulation. , Föller M., FASEB J. October 1, 2012; 26 (10): 4243-53.
Selective interaction of syntaxin 1A with KCNQ2: possible implications for specific modulation of presynaptic activity. , Regev N., PLoS One. August 13, 2009; 4 (8): e6586.
Modulation of potassium channel function confers a hyperproliferative invasive phenotype on embryonic stem cells. , Morokuma J., Proc Natl Acad Sci U S A. October 28, 2008; 105 (43): 16608-13.
Upregulation of KCNE1 induces QT interval prolongation in patients with chronic heart failure. , Watanabe E., Circ J. April 1, 2007; 71 (4): 471-8.
Regulation of endocytic recycling of KCNQ1/ KCNE1 potassium channels. , Seebohm G ., Circ Res. March 16, 2007; 100 (5): 686-92.
The role of S4 charges in voltage-dependent and voltage-independent KCNQ1 potassium channel complexes. , Panaghie G., J Gen Physiol. February 1, 2007; 129 (2): 121-33.
Ancillary subunits and stimulation frequency determine the potency of chromanol 293B block of the KCNQ1 potassium channel. , Bett GC., J Physiol. November 1, 2006; 576 (Pt 3): 755-67.
Functional coassembly of KCNQ4 with KCNE-beta- subunits in Xenopus oocytes. , Strutz-Seebohm N., Cell Physiol Biochem. January 1, 2006; 18 (1-3): 57-66.
The KCNQ5 potassium channel from mouse: a broadly expressed M-current like potassium channel modulated by zinc, pH, and volume changes. , Jensen HS., Brain Res Mol Brain Res. September 13, 2005; 139 (1): 52-62.
KCNE3 truncation mutants reveal a bipartite modulation of KCNQ1 K+ channels. , Gage SD., J Gen Physiol. December 1, 2004; 124 (6): 759-71.
Functional coupling between heterologously expressed dopamine D(2) receptors and KCNQ channels. , Ljungstrom T., Pflugers Arch. September 1, 2003; 446 (6): 684-94.
Novel gene hKCNE4 slows the activation of the KCNQ1 channel. , Teng S., Biochem Biophys Res Commun. April 11, 2003; 303 (3): 808-13.
Molecular and functional characterization of s- KCNQ1 potassium channel from rectal gland of Squalus acanthias. , Waldegger S., Pflugers Arch. January 1, 1999; 437 (2): 298-304.
Functional expression of two KvLQT1-related potassium channels responsible for an inherited idiopathic epilepsy. , Yang WP., J Biol Chem. July 31, 1998; 273 (31): 19419-23.