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Summary Expression Phenotypes Gene Literature (35) GO Terms (3) Nucleotides (53) Proteins (43) Interactants (29) Wiki
XB-GENEPAGE-6033379

Papers associated with asic2



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Molecular profiling of CO2/pH-sensitive neurons in the locus coeruleus of bullfrogs reveals overlapping noradrenergic and glutamatergic cell identity., Amaral-Silva L, Santin JM., Comp Biochem Physiol A Mol Integr Physiol. September 1, 2023; 283 111453.            


Mambalgin-2 Induces Cell Cycle Arrest and Apoptosis in Glioma Cells via Interaction with ASIC1a., Bychkov M, Shulepko M, Osmakov D, Andreev Y, Sudarikova A, Vasileva V, Pavlyukov MS, Latyshev YA, Potapov AA, Kirpichnikov M, Shenkarev ZO, Lyukmanova E., Cancers (Basel). July 8, 2020; 12 (7):                       


A valve-like mechanism controls desensitization of functional mammalian isoforms of acid-sensing ion channels., Wu Y, Chen Z, Canessa CM., Elife. May 2, 2019; 8               


Shear force modulates the activity of acid-sensing ion channels at low pH or in the presence of non-proton ligands., Barth D, Fronius M., Sci Rep. May 1, 2019; 9 (1): 6781.                  


Inhalational anesthetics accelerate desensitization of acid-sensing ion channels., Lehmke L, Coburn M, Möller M, Blaumeiser-Debarry R, Lenzig P, Wiemuth D, Gründer S., Neuropharmacology. June 1, 2018; 135 496-505.


The ASIC3/P2X3 cognate receptor is a pain-relevant and ligand-gated cationic channel., Stephan G, Huang L, Tang Y, Vilotti S, Fabbretti E, Yu Y, Nörenberg W, Franke H, Gölöncsér F, Sperlágh B, Dopychai A, Hausmann R, Schmalzing G, Rubini P, Illes P., Nat Commun. April 10, 2018; 9 (1): 1354.                    


Proton-independent activation of acid-sensing ion channel 3 by an alkaloid, lindoldhamine, from Laurus nobilis., Osmakov DI, Koshelev SG, Andreev YA, Dubinnyi MA, Kublitski VS, Efremov RG, Sobolevsky AI, Kozlov SA., Br J Pharmacol. March 1, 2018; 175 (6): 924-937.


Molecular Basis for Allosteric Inhibition of Acid-Sensing Ion Channel 1a by Ibuprofen., Lynagh T, Romero-Rojo JL, Lund C, Pless SA., J Med Chem. October 12, 2017; 60 (19): 8192-8200.


Functional and pharmacological characterization of two different ASIC1a/2a heteromers reveals their sensitivity to the spider toxin PcTx1., Joeres N, Augustinowski K, Neuhof A, Assmann M, Gründer S., Sci Rep. June 9, 2016; 6 27647.              


The Thumb Domain Mediates Acid-sensing Ion Channel Desensitization., Krauson AJ, Carattino MD., J Biol Chem. May 20, 2016; 291 (21): 11407-19.


Optogenetic approaches addressing extracellular modulation of neural excitability., Ferenczi EA, Vierock J, Atsuta-Tsunoda K, Tsunoda SP, Ramakrishnan C, Gorini C, Thompson K, Lee SY, Berndt A, Perry C, Minniberger S, Vogt A, Mattis J, Prakash R, Delp S, Deisseroth K, Hegemann P., Sci Rep. January 22, 2016; 6 23947.                


Xenopus borealis as an alternative source of oocytes for biophysical and pharmacological studies of neuronal ion channels., Cristofori-Armstrong B, Soh MS, Talwar S, Brown DL, Griffin JD, Dekan Z, Stow JL, King GF, Lynch JW, Rash LD., Sci Rep. January 12, 2015; 5 14763.                                


Acid-sensing ion channel (ASIC) 1a/2a heteromers have a flexible 2:1/1:2 stoichiometry., Bartoi T, Augustinowski K, Polleichtner G, Gründer S, Ulbrich MH., Proc Natl Acad Sci U S A. June 3, 2014; 111 (22): 8281-6.


Black mamba venom peptides target acid-sensing ion channels to abolish pain., Diochot S, Baron A, Salinas M, Douguet D, Scarzello S, Dabert-Gay AS, Debayle D, Friend V, Alloui A, Lazdunski M, Lingueglia E., Nature. October 25, 2012; 490 (7421): 552-5.


A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain., Bohlen CJ, Chesler AT, Sharif-Naeini R, Medzihradszky KF, Zhou S, King D, Sánchez EE, Burlingame AL, Basbaum AI, Julius D., Nature. November 16, 2011; 479 (7373): 410-4.      


Cross-reactivity of acid-sensing ion channel and Na⁺-H⁺ exchanger antagonists with nicotinic acetylcholine receptors., Santos-Torres J, Ślimak MA, Auer S, Ibañez-Tallon I., J Physiol. November 1, 2011; 589 (Pt 21): 5109-23.


Heteromeric acid-sensing ion channels (ASICs) composed of ASIC2b and ASIC1a display novel channel properties and contribute to acidosis-induced neuronal death., Sherwood TW, Lee KG, Gormley MG, Askwith CC., J Neurosci. June 29, 2011; 31 (26): 9723-34.


Proteolytic cleavage of human acid-sensing ion channel 1 by the serine protease matriptase., Clark EB, Jovov B, Rooj AK, Fuller CM, Benos DJ., J Biol Chem. August 27, 2010; 285 (35): 27130-43.


Identification of protein domains that control proton and calcium sensitivity of ASIC1a., Sherwood T, Franke R, Conneely S, Joyner J, Arumugan P, Askwith C., J Biol Chem. October 9, 2009; 284 (41): 27899-27907.


Nafamostat mesilate reversibly blocks acid-sensing ion channel currents., Ugawa S, Ishida Y, Ueda T, Inoue K, Nagao M, Shimada S., Biochem Biophys Res Commun. November 9, 2007; 363 (1): 203-8.


Cleft-type cyclophanes confer neuroprotection against excitatory neurotoxicity in vitro and in vivo through inhibition of NMDA receptors., Masuko T, Nemoto Y, Nagaoka H, Miyake M, Kizawa Y, Kusama-Eguchi K, Kashiwagi K, Igarashi K, Kusama T., Neuropharmacology. September 1, 2007; 53 (4): 515-23.


The receptor site of the spider toxin PcTx1 on the proton-gated cation channel ASIC1a., Salinas M, Rash LD, Baron A, Lambeau G, Escoubas P, Lazdunski M., J Physiol. January 15, 2006; 570 (Pt 2): 339-54.


Design and synthesis of a novel water-soluble NMDA receptor antagonist with a 1,4,7,10-tetraazacyclododecane group., Masuko T, Metori K, Kizawa Y, Kusama T, Miyake M., Chem Pharm Bull (Tokyo). April 1, 2005; 53 (4): 444-7.


Selective regulation of acid-sensing ion channel 1 by serine proteases., Poirot O, Vukicevic M, Boesch A, Kellenberger S., J Biol Chem. September 10, 2004; 279 (37): 38448-57.


Knockout of the ASIC2 channel in mice does not impair cutaneous mechanosensation, visceral mechanonociception and hearing., Roza C, Puel JL, Kress M, Baron A, Diochot S, Lazdunski M, Waldmann R., J Physiol. July 15, 2004; 558 (Pt 2): 659-69.


A new sea anemone peptide, APETx2, inhibits ASIC3, a major acid-sensitive channel in sensory neurons., Diochot S, Baron A, Rash LD, Deval E, Escoubas P, Scarzello S, Salinas M, Lazdunski M., EMBO J. April 7, 2004; 23 (7): 1516-25.


Amiloride-insensitive currents of the acid-sensing ion channel-2a (ASIC2a)/ASIC2b heteromeric sour-taste receptor channel., Ugawa S, Yamamoto T, Ueda T, Ishida Y, Inagaki A, Nishigaki M, Shimada S., J Neurosci. May 1, 2003; 23 (9): 3616-22.


Single channel properties of rat acid-sensitive ion channel-1alpha, -2a, and -3 expressed in Xenopus oocytes., Zhang P, Canessa CM., J Gen Physiol. October 1, 2002; 120 (4): 553-66.                    


Up-regulation of acid-gated Na(+) channels (ASICs) by cystic fibrosis transmembrane conductance regulator co-expression in Xenopus oocytes., Ji HL, Jovov B, Fu J, Bishop LR, Mebane HC, Fuller CM, Stanton BA, Benos DJ., J Biol Chem. March 8, 2002; 277 (10): 8395-405.


Functional implications of the localization and activity of acid-sensitive channels in rat peripheral nervous system., Alvarez de la Rosa D, Zhang P, Shao D, White F, Canessa CM., Proc Natl Acad Sci U S A. February 19, 2002; 99 (4): 2326-31.


Selective modulation of heteromeric ASIC proton-gated channels by neuropeptide FF., Catarsi S, Babinski K, Séguéla P., Neuropharmacology. October 1, 2001; 41 (5): 592-600.


Zn2+ and H+ are coactivators of acid-sensing ion channels., Baron A, Schaefer L, Lingueglia E, Champigny G, Lazdunski M., J Biol Chem. September 21, 2001; 276 (38): 35361-7.


Single-channel properties of recombinant acid-sensitive ion channels formed by the subunits ASIC2 and ASIC3 from dorsal root ganglion neurons expressed in Xenopus oocytes., Zhang P, Canessa CM., J Gen Physiol. June 1, 2001; 117 (6): 563-72.                      


Mammalian ASIC2a and ASIC3 subunits co-assemble into heteromeric proton-gated channels sensitive to Gd3+., Babinski K, Catarsi S, Biagini G, Séguéla P., J Biol Chem. September 15, 2000; 275 (37): 28519-25.


Tetraethylammonium block of the BNC1 channel., Adams CM, Price MP, Snyder PM, Welsh MJ., Biophys J. March 1, 1999; 76 (3): 1377-83.

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