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19th International Xenopus Conference Meeting Report: Latest developments and future perspectives. , Zhou C , Kulkarni S ., Dev Dyn. February 1, 2024; 253 (2): 272-276.
Adipose tissue derived stem cell secretome induces motor and histological gains after complete spinal cord injury in Xenopus laevis and mice. , Assunção-Silva RC, Pinho A, Cibrão JR, Pereira IM, Monteiro S, Silva NA, Campos J, Rebelo AL, Schlosser G , Pinto L, Pandit A, Salgado AJ., J Tissue Eng. January 1, 2024; 15 20417314231203824.
Critical contribution of the intracellular C-terminal region to TRESK channel activity is revealed by the epithelial Na+ current ratio method. , Debreczeni D, Baukál D, Pergel E, Veres I, Czirják G., J Biol Chem. June 1, 2023; 299 (6): 104737.
Structure of a eukaryotic cholinephosphotransferase-1 reveals mechanisms of substrate recognition and catalysis. , Wang L, Zhou M., Nat Commun. May 13, 2023; 14 (1): 2753.
Do Amino Acid Antiporters Have Asymmetric Substrate Specificity? , Gauthier-Coles G, Fairweather SJ, Bröer A, Bröer S., Biomolecules. February 6, 2023; 13 (2):
Flux coupling, not specificity, shapes the transport and phylogeny of SLC6 glycine transporters. , Le Guellec B, Rousseau F, Bied M, Supplisson S., Proc Natl Acad Sci U S A. October 11, 2022; 119 (41): e2205874119.
Human Melanocortin-2 Receptor: Identifying a Role for Residues in the TM4, EC2, and TM5 Domains in Activation and Trafficking as a Result of Co-Expression with the Accessory Protein, Mrap1 in Chinese Hamster Ovary Cells. , Davis PV, Shaughnessy CA, Dores RM., Biomolecules. October 4, 2022; 12 (10):
Bupivacaine as a euthanasia agent for African Clawed Frogs (Xenopus laevis). , Navarro K, Jampachaisri K, Chu D, Pacharinsak C., PLoS One. January 1, 2022; 17 (12): e0279331.
Molecular architecture of the luminal ring of the Xenopus laevis nuclear pore complex. , Zhang Y , Li S, Zeng C, Huang G, Zhu X, Wang Q, Wang K, Zhou Q, Yan C, Zhang W, Yang G, Liu M, Tao Q , Tao Q , Lei J, Shi Y ., Cell Res. June 1, 2020; 30 (6): 532-540.
Identifying Common Features in the Activation of Melanocortin-2 Receptors: Studies on the Xenopus tropicalis Melanocortin-2 Receptor. , Davis PE, Wilkinson EC, Dores RM., Int J Mol Sci. August 26, 2019; 20 (17):
Functional analysis of a triplet deletion in the gene encoding the sodium glucose transporter 3, a potential risk factor for ADHD. , Schäfer N, Friedrich M, Jørgensen ME, Kollert S, Koepsell H, Wischmeyer E, Lesch KP, Geiger D, Döring F., PLoS One. October 4, 2018; 13 (10): e0205109.
Effects of trimethoprim-sulfadiazine and detomidine on the function of equine Kv 11.1 channels in a two-electrode voltage-clamp (TEVC) oocyte model. , Trachsel DS, Tejada MA, Groesfjeld Christensen V, Pedersen PJ, Kanters JK, Buhl R, Calloe K, Klaerke DA., J Vet Pharmacol Ther. August 1, 2018; 41 (4): 536-545.
Point mutation of a conserved aspartate, D69, in the muscarinic M 2 receptor does not modify voltage-sensitive agonist potency. , Ågren R, Sahlholm K, Nilsson J, Århem P., Biochem Biophys Res Commun. January 29, 2018; 496 (1): 101-104.
Ivermectin activates GIRK channels in a PIP2 -dependent, Gβγ -independent manner and an amino acid residue at the slide helix governs the activation. , Chen IS, Tateyama M, Fukata Y, Uesugi M, Kubo Y., J Physiol. September 1, 2017; 595 (17): 5895-5912.
Substituted cysteine accessibility method (SCAM) analysis of the transport domain of human concentrative nucleoside transporter 3 (hCNT3) and other family members reveals features of structural and functional importance. , Mulinta R, Yao SYM, Ng AML, Cass CE, Young JD., J Biol Chem. June 9, 2017; 292 (23): 9505-9522.
Two classes of regulatory subunits coassemble in the same BK channel and independently regulate gating. , Gonzalez-Perez V, Xia XM, Lingle CJ., Nat Commun. September 21, 2015; 6 8341.
The Role of Flexible Loops in Folding, Trafficking and Activity of Equilibrative Nucleoside Transporters. , Aseervatham J, Tran L, Machaca K , Boudker O., PLoS One. September 1, 2015; 10 (9): e0136779.
The Inner Nuclear Membrane Protein Nemp1 Is a New Type of RanGTP-Binding Protein in Eukaryotes. , Shibano T, Mamada H, Hakuno F, Takahashi S , Taira M ., PLoS One. May 6, 2015; 10 (5): e0127271.
Molecular cloning, expression, and signaling pathway of four melanin-concentrating hormone receptors from Xenopus tropicalis. , Kobayashi Y, Hamamoto A, Hirayama T, Saito Y., Gen Comp Endocrinol. February 1, 2015; 212 114-23.
A novel PKD2L1 C-terminal domain critical for trimerization and channel function. , Zheng W, Hussein S, Yang J , Huang J, Zhang F, Hernandez-Anzaldo S, Fernandez-Patron C, Cao Y , Cao Y , Zeng H, Tang J, Chen XZ., Sci Rep. January 12, 2015; 5 9460.
The ORF4a protein of human coronavirus 229E functions as a viroporin that regulates viral production. , Zhang R, Wang K, Lv W, Yu W, Xie S, Xu K, Schwarz W, Xiong S, Sun B., Biochim Biophys Acta. April 1, 2014; 1838 (4): 1088-95.
Both transmembrane domains of BK β1 subunits are essential to confer the normal phenotype of β1-containing BK channels. , Kuntamallappanavar G, Toro L, Dopico AM., PLoS One. January 1, 2014; 9 (10): e109306.
The SLC16 gene family - structure, role and regulation in health and disease. , Halestrap AP., Mol Aspects Med. January 1, 2013; 34 (2-3): 337-49.
Arg188 in rice sucrose transporter OsSUT1 is crucial for substrate transport. , Sun Y, Ward JM., BMC Biochem. November 21, 2012; 13 26.
Effect of simultaneously replacing putative TM6 and TM12 of human NBCe1-A with those from NBCn1 on surface abundance in Xenopus oocytes. , Chen LM, Qin X, Moss FJ, Liu Y , Boron WF., J Membr Biol. March 1, 2012; 245 (3): 131-40.
The intracellular amino terminus plays a dominant role in desensitization of ATP-gated P2X receptor ion channels. , Allsopp RC, Evans RJ., J Biol Chem. December 30, 2011; 286 (52): 44691-701.
The inhibition of monocarboxylate transporter 2 ( MCT2) by AR-C155858 is modulated by the associated ancillary protein. , Ovens MJ, Manoharan C, Wilson MC, Murray CM, Halestrap AP., Biochem J. October 15, 2010; 431 (2): 217-25.
AR-C155858 is a potent inhibitor of monocarboxylate transporters MCT1 and MCT2 that binds to an intracellular site involving transmembrane helices 7-10. , Ovens MJ, Davies AJ, Wilson MC, Murray CM, Halestrap AP., Biochem J. January 15, 2010; 425 (3): 523-30.
Cystic fibrosis transmembrane conductance regulator: using differential reactivity toward channel-permeant and channel-impermeant thiol-reactive probes to test a molecular model for the pore. , Alexander C, Ivetac A, Liu X, Norimatsu Y, Serrano JR, Landstrom A, Sansom M, Dawson DC., Biochemistry. October 27, 2009; 48 (42): 10078-88.
Roles of ectodomain and transmembrane regions in ethanol and agonist action in purinergic P2X2 and P2X3 receptors. , Asatryan L, Popova M, Woodward JJ, King BF , Alkana RL, Davies DL., Neuropharmacology. October 1, 2008; 55 (5): 835-43.
Structural signatures and membrane helix 4 in GLUT1: inferences from human blood- brain glucose transport mutants. , Pascual JM, Wang D, Yang R, Shi L, Yang H, De Vivo DC., J Biol Chem. June 13, 2008; 283 (24): 16732-42.
Presence of aquaporin and V-ATPase on the contractile vacuole of Amoeba proteus. , Nishihara E, Yokota E, Tazaki A , Orii H, Katsuhara M, Kataoka K, Igarashi H, Moriyama Y , Shimmen T, Sonobe S., Biol Cell. March 1, 2008; 100 (3): 179-88.
The Xenopus FcR family demonstrates continually high diversification of paired receptors in vertebrate evolution. , Guselnikov SV , Ramanayake T, Erilova AY, Mechetina LV, Najakshin AM, Robert J , Taranin AV., BMC Evol Biol. February 8, 2008; 8 148.
A conductive pathway generated from fragments of the human red cell anion exchanger AE1. , Parker MD , Young MT, Daly CM, Meech RW, Boron WF, Tanner MJ., J Physiol. May 15, 2007; 581 (Pt 1): 33-50.
Ivermectin Interaction with transmembrane helices reveals widespread rearrangements during opening of P2X receptor channels. , Silberberg SD, Li M, Swartz KJ., Neuron. April 19, 2007; 54 (2): 263-74.
Specific mutations in transmembrane helix 8 of human concentrative Na+/nucleoside cotransporter hCNT1 affect permeant selectivity and cation coupling. , Slugoski MD, Loewen SK, Ng AM, Smith KM, Yao SY, Karpinski E, Cass CE, Baldwin SA, Young JD., Biochemistry. February 13, 2007; 46 (6): 1684-93.
Recent progress in structure-function analyses of Nramp proton-dependent metal-ion transporters. , Courville P, Chaloupka R, Cellier MF., Biochem Cell Biol. December 1, 2006; 84 (6): 960-78.
Secondary structure and gating rearrangements of transmembrane segments in rat P2X4 receptor channels. , Silberberg SD, Chang TH, Swartz KJ., J Gen Physiol. April 1, 2005; 125 (4): 347-59.
Mutational analysis of the alpha-1 repeat of the cardiac Na(+)-Ca2+ exchanger. , Ottolia M, Nicoll DA, Philipson KD., J Biol Chem. January 14, 2005; 280 (2): 1061-9.
The amino acid transporter asc-1 is not involved in cystinuria. , Pineda M, Font M, Bassi MT, Manzoni M, Borsani G, Marigo V, Fernández E, Río RM, Purroy J, Zorzano A, Nunes V, Palacín M., Kidney Int. October 1, 2004; 66 (4): 1453-64.
Cross-linking of glycine receptor transmembrane segments two and three alters coupling of ligand binding with channel opening. , Lobo IA, Trudell JR, Harris RA., J Neurochem. August 1, 2004; 90 (4): 962-9.
Cation stoichiometry and cation pathway in the Na, K-ATPase and nongastric H, K-ATPase. , Horisberger JD, Guennoun S, Burnay M, Geering K., Ann N Y Acad Sci. April 1, 2003; 986 127-32.
Analysis of the differential modulation of sulphonylurea block of beta-cell and cardiac ATP-sensitive K+ (K(ATP)) channels by Mg-nucleotides. , Reimann F, Dabrowski M, Jones P, Gribble FM, Ashcroft FM., J Physiol. February 15, 2003; 547 (Pt 1): 159-68.
Cooperativity and flexibility of cystic fibrosis transmembrane conductance regulator transmembrane segments participate in membrane localization of a charged residue. , Carveth K, Buck T, Anthony V, Skach WR., J Biol Chem. October 18, 2002; 277 (42): 39507-14.
Functional and molecular characterization of nucleobase transport by recombinant human and rat equilibrative nucleoside transporters 1 and 2. Chimeric constructs reveal a role for the ENT2 helix 5-6 region in nucleobase translocation. , Yao SY, Ng AM, Vickers MF, Sundaram M, Cass CE, Baldwin SA, Young JD., J Biol Chem. July 12, 2002; 277 (28): 24938-48.
Identification of a novel Na+-independent acidic amino acid transporter with structural similarity to the member of a heterodimeric amino acid transporter family associated with unknown heavy chains. , Matsuo H, Kanai Y, Kim JY , Chairoungdua A, Kim DK, Inatomi J, Shigeta Y, Ishimine H, Chaekuntode S, Tachampa K, Choi HW, Babu E, Fukuda J, Endou H., J Biol Chem. June 7, 2002; 277 (23): 21017-26.
Characterisation and cloning of a Na(+)-dependent broad-specificity neutral amino acid transporter from NBL-1 cells: a novel member of the ASC/B(0) transporter family. , Pollard M, Meredith D, McGivan JD., Biochim Biophys Acta. April 12, 2002; 1561 (2): 202-8.
The oxidant thimerosal modulates gating behavior of KCNQ1 by interaction with the channel outer shell. , Kerst G, Brousos H, Schreiber R, Nitschke R, Hug MJ, Greger R, Bleich M., J Membr Biol. March 15, 2002; 186 (2): 89-100.
Identification and characterization of a novel member of the heterodimeric amino acid transporter family presumed to be associated with an unknown heavy chain. , Chairoungdua A, Kanai Y, Matsuo H, Inatomi J, Kim DK, Endou H., J Biol Chem. December 28, 2001; 276 (52): 49390-9.
A disulfide bond is required for functional assembly of NCX1 from complementary fragments. , Qiu Z, Chen J , Nicoll DA, Philipson KD., Biochem Biophys Res Commun. October 5, 2001; 287 (4): 825-8.