sp8 Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-1216188

Gene Symbol: sp8 Gene Name: Sp8 transcription factor

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: sp8 assayed (6 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (43 sources): abnormal anal canal morphology, abnormal apical ectodermal ridge morphology, abnormal basal ganglion morphology, abnormal brain internal capsule morphology, abnormal caudal vertebrae morphology, abnormal cortical plate morphology, abnormal craniofacial morphology, abnormal forebrain development, abnormal forelimb bud morphology, abnormal forelimb morphology, abnormal genital tubercle morphology, abnormal hindlimb morphology, abnormal humerus morphology, abnormal limb development, abnormal limb morphology, abnormal lumbar vertebrae morphology, abnormal neuronal precursor proliferation, abnormal olfactory bulb development, abnormal olfactory bulb external plexiform layer morphology, abnormal olfactory bulb glomerular layer morphology, abnormal olfactory bulb internal plexiform layer morphology, abnormal olfactory bulb layer morphology, abnormal palate morphology, abnormal perineum morphology, abnormal tail morphology, abnormal telencephalon development, absent caudal vertebrae, absent cerebellum, absent sacral vertebrae, absent tail, caudal body truncation, forebrain hypoplasia, genital tubercle hypoplasia, incomplete caudal neuropore closure, incomplete rostral neuropore closure, increased neuron apoptosis, kinked tail, limbs/digits/tail phenotype, neonatal lethality, complete penetrance, nervous system phenotype, perinatal lethality, complete penetrance, small olfactory bulb, thin cortical plate [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (43 sources): abnormal anal canal morphology, abnormal apical ectodermal ridge morphology, abnormal basal ganglion morphology, abnormal brain internal capsule morphology, abnormal caudal vertebrae morphology, abnormal cortical plate morphology, abnormal craniofacial morphology, abnormal forebrain development, abnormal forelimb bud morphology, abnormal forelimb morphology, [+]