Monarch Ortholog Phenotypes
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Mouse (21 sources):
abnormal CNS synaptic transmission,
abnormal amino acid level,
abnormal inhibitory synapse morphology,
abnormal miniature excitatory postsynaptic currents,
abnormal miniature inhibitory postsynaptic currents,
abnormal social investigation,
abnormal symmetric synapse morphology,
abnormal synaptic bouton morphology,
abnormal synaptic vesicle number,
abnormal translation,
decreased locomotor activity,
decreased vertical activity,
embryonic lethality, complete penetrance,
excessive vocalization,
increased gonadal fat pad weight,
increased phenylalanine level,
increased serine level,
limb grasping,
nervous system phenotype,
preweaning lethality, complete penetrance,
short stride length
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