ppard Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-481494

Gene Symbol: ppard Gene Name: peroxisome proliferator activated receptor delta

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: ppard assayed (5 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (77 sources): abnormal basal ganglion morphology, abnormal cerebral cortex morphology, abnormal compact bone volume, abnormal epidermis stratum corneum morphology, abnormal extraembryonic tissue morphology, abnormal fat cell morphology, abnormal gonadal fat pad morphology, abnormal hair follicle development, abnormal hair follicle peg morphology, abnormal keratinocyte adhesion, abnormal keratinocyte morphology, abnormal lipid level, abnormal medium spiny neuron morphology, abnormal mitochondrial ATP synthesis coupled electron transport, abnormal motor capabilities/coordination/movement, abnormal muscle cell glucose uptake, abnormal placenta development, abnormal response to cardiac infarction, abnormal response to exercise, abnormal response to novel object, abnormal skin condition, abnormal stratum corneum lipid matrix formation, adipose tissue phenotype, cardiovascular system phenotype, decreased abdominal fat pad weight, decreased aerobic running capacity, decreased body size, decreased bone mineral density of femur, decreased bone stiffness, decreased bone strength, decreased bone volume, decreased brain size, decreased cardiac muscle contractility, decreased cholesterol level, decreased dopaminergic neuron number, decreased energy dissipated prior to femur fracture, decreased exploration in new environment, decreased fetal size, decreased grip strength, decreased interscapular fat pad weight, decreased keratinocyte proliferation, decreased lean body mass, decreased liver cholesterol level, decreased liver triglyceride level, decreased mesenteric fat pad weight, decreased mitochondrial size, decreased myocardial infarct size, decreased neuron number, decreased placental labyrinth size, decreased skeletal muscle mass, decreased thermal nociceptive threshold, delayed wound healing, embryonic growth retardation, embryonic lethality during organogenesis, incomplete penetrance, epidermal hyperplasia, homeostasis/metabolism phenotype, impaired osteoblast differentiation, increased bone marrow adipose tissue amount, increased cardiac cell glucose uptake, increased cardiac muscle glycogen level, increased fatty acids level, increased incidence of tumors by chemical induction, increased keratinocyte apoptosis, increased keratinocyte proliferation, increased osteoclast cell number, increased skin papilloma incidence, increased skin tumor incidence, increased total body fat amount, increased tumor incidence, limb grasping, prenatal lethality, prenatal lethality, complete penetrance, prenatal lethality, incomplete penetrance, reduced fertility, short stride length, thin hypodermis, underdeveloped hair follicles [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (77 sources): abnormal basal ganglion morphology, abnormal cerebral cortex morphology, abnormal compact bone volume, abnormal epidermis stratum corneum morphology, abnormal extraembryonic tissue morphology, abnormal fat cell morphology, abnormal gonadal fat pad morphology, abnormal hair follicle development, abnormal hair follicle peg morphology, abnormal keratinocyte adhesion, [+]