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XB-GENEPAGE-486161
pitx3 paired like homeodomain 3
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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abnormal determination of left/right symmetry (1 source), abnormal developmental process (1 source), abnormal nodal signaling pathway (1 source), abnormally laterally curved whole organism (1 source), decreased size of the eye primordium (1 source) |
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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Manual annotations: pitx3 manipulated (28 sources) |
Computed annotations: pitx3 assayed (5 sources) |
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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Xla Wt + pitx3 MO (22 sources), Xla Wt + pitx3 MO (7 sources) |
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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Human (13 sources): Blindness, Cataract, Chorea, Intellectual disability, Microcornea, Microphthalmia, Ocular anterior segment dysgenesis, Ocular hypertension, Opacification of the corneal stroma, Peters anomaly, [+] |
Mouse (55 sources): abnormal breathing pattern, abnormal coping response, abnormal dorsal striatum morphology, abnormal eye distance/ position, abnormal food intake, abnormal grip strength, abnormal heart rate, abnormal lens development, abnormal locomotor activation, abnormal locomotor behavior, [+] |
View all ortholog results at Monarch |