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XB-GENEPAGE-5823108
nup93 nucleoporin 93kDa
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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| abnormally decreased number of cilium in the left-right organizer (3 sources), abnormally decreased number of cilium in the multiciliated epidermal cell (2 sources), abnormal heart looping (1 source), abnormal heart morphology (1 source), abnormal multiciliated cell (1 source), abnormal multiciliated epidermal cell (1 source), abnormally localised basal body (1 source), absent cilium (1 source), obsolete abnormal cilium motility (1 source) |
| Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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| Manual annotations: nup93 manipulated (3 sources) |
| Diseases
Diseases from the human disease ontology (DO) manually associated with phenotypes
from disease models. Sources are grouped by anatomical (AP) and expression (EP) phenotypes.
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| congenital heart disease (7AP sources, 3 EP sources), visceral heterotaxy (7AP sources, 3 EP sources), ciliopathy (2AP sources) |
| Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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| Xtr Wt + nup93 MO (6 sources), Xtr wt + nup93 MO (2 sources), Xtr Wt + nup93 MO (2 sources), Xtr Wt + nup93 MO (1 source), Xtr Wt + nup93 MO (1 source) |
| Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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| Human (5 sources): Diffuse mesangial sclerosis, Focal segmental glomerulosclerosis, Hematuria, Stage 5 chronic kidney disease, Steroid-resistant nephrotic syndrome |
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View all ortholog results at Monarch |