| Monarch Ortholog Phenotypes
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Human (1 source):
Sepsis
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Mouse (23 sources):
abnormal Ammon gyrus morphology,
abnormal bile duct morphology,
abnormal cortical ventricular zone morphology,
abnormal dentate gyrus morphology,
abnormal epidermis stratum corneum morphology,
abnormal hepatoblast differentiation,
abnormal lung alveolus development,
abnormal neuron differentiation,
abnormal neuronal precursor proliferation,
abnormal plasma membrane morphology,
abnormal pulmonary alveolar sac morphology,
abnormal pulmonary interalveolar septum morphology,
abnormal surfactant physiology,
cellular phenotype,
decreased body size,
decreased liver glycogen level,
decreased neuronal precursor cell number,
embryonic lethality, complete penetrance,
impaired skin barrier function,
neonatal lethality, complete penetrance,
no abnormal phenotype detected,
postnatal lethality, complete penetrance,
premature death
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.