pik3c3 Phenotypes

Phenotypes

XB-GENEPAGE-6085225

Gene Symbol: pik3c3 Gene Name: phosphatidylinositol 3-kinase catalytic subunit type 3

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (39 sources): abnormal CD4-positive, alpha beta T cell morphology, abnormal CD8-positive, alpha beta T cell morphology, abnormal autophagy, abnormal cell morphology, abnormal embryonic epiblast morphology, abnormal lens fiber morphology, abnormal mitochondrial physiology, abnormal proprioceptive neuron morphology, abnormal sensory neuron morphology, abnormal visceral endoderm morphology, absent mesoderm, cellular phenotype, decreased CD4-positive, alpha beta T cell number, decreased body size, decreased cardiac muscle contractility, decreased cell proliferation, decreased circulating aspartate transaminase level, decreased embryo size, decreased grip strength, decreased liver glycogen level, decreased sensory neuron number, disorganized embryonic tissue, embryonic growth arrest, embryonic growth retardation, embryonic lethality between implantation and placentation, complete penetrance, failure of primitive streak formation, failure to gastrulate, hindlimb paralysis, immune system phenotype, impaired autophagy, increased T cell apoptosis, increased heart weight, increased left ventricle weight, increased neuron apoptosis, no abnormal phenotype detected, oxidative stress, pale liver, postnatal lethality, complete penetrance, premature death [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (39 sources): abnormal CD4-positive, alpha beta T cell morphology, abnormal CD8-positive, alpha beta T cell morphology, abnormal autophagy, abnormal cell morphology, abnormal embryonic epiblast morphology, abnormal lens fiber morphology, abnormal mitochondrial physiology, abnormal proprioceptive neuron morphology, abnormal sensory neuron morphology, abnormal visceral endoderm morphology, [+]