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XB-GENEPAGE-949625
traf7 TNF receptor associated factor 7
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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| abnormal head morphology (7 sources), abnormal cilium morphology (6 sources), abnormal cilium motility (4 sources), abnormal multiciliated cell (4 sources), abnormal tail morphology (4 sources), edematous head (4 sources), abnormally decreased number of cilium in the left-right organizer (3 sources), abnormally decreased number of cilium in the multiciliated cell (3 sources), edematous heart (3 sources), increased size of the pronephric kidney (3 sources), abnormal cerebrospinal fluid (2 sources), abnormal chondrocranium morphology (2 sources), abnormal cilium morphology in the pronephric kidney (2 sources), abnormal foregut morphology (2 sources), abnormal heart looping (2 sources), abnormal heart morphology (2 sources), abnormal pronephric kidney morphology (2 sources), decreased size of the cilium (2 sources), edematous brain (2 sources), abnormal heart contraction (1 source), abnormal transporting epithelium (1 source) |
| Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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| Manual annotations: traf7 manipulated (4 sources) |
| Diseases
Diseases from the human disease ontology (DO) manually associated with phenotypes
from disease models. Sources are grouped by anatomical (AP) and expression (EP) phenotypes.
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| cystic kidney disease (2AP sources) |
| Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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| Xtr wt + traf7 MO (16 sources), Xtr Wt + traf7 CRISPR (10 sources) |
| Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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| Human (29 sources): Abnormal facial shape, Abnormal heart morphology, Abnormal pinna morphology, Cerebral atrophy, Cerebral visual impairment, Clinodactyly, Coarctation of aorta, Cystic hygroma, Delayed speech and language development, Double outlet right ventricle, [+] |
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View all ortholog results at Monarch |