sptssb Phenotypes

Phenotypes

XB-GENEPAGE-950652

Gene Symbol: sptssb Gene Name: serine palmitoyltransferase small subunit B

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: sptssb assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (11 sources): abnormal cerebellum white matter morphology, abnormal coat appearance, abnormal endoplasmic reticulum stress, abnormal lipid homeostasis, abnormal retina inner plexiform layer morphology, abnormal retina outer plexiform layer morphology, brain vacuoles, decreased circulating glucose level, decreased fasting circulating glucose level, optic nerve degeneration, premature death [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (11 sources): abnormal cerebellum white matter morphology, abnormal coat appearance, abnormal endoplasmic reticulum stress, abnormal lipid homeostasis, abnormal retina inner plexiform layer morphology, abnormal retina outer plexiform layer morphology, brain vacuoles, decreased circulating glucose level, decreased fasting circulating glucose level, optic nerve degeneration, [+]