prmt5 Phenotypes

XB-GENEPAGE-975033

Gene Symbol: prmt5 Gene Name: protein arginine methyltransferase 5

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: prmt5 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (16 sources): abnormal cerebellum external granule cell layer morphology, abnormal cortical plate morphology, abnormal cortical ventricular zone morphology, abnormal embryonic/fetal subventricular zone morphology, abnormal neuronal precursor proliferation, absent inner cell mass proliferation, decreased brain size, decreased brain weight, decreased embryo size, embryonic growth retardation, embryonic lethality, complete penetrance, enlarged lateral ventricles, impaired balance, increased neuron apoptosis, postnatal lethality, complete penetrance, thin cerebral cortex [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (16 sources): abnormal cerebellum external granule cell layer morphology, abnormal cortical plate morphology, abnormal cortical ventricular zone morphology, abnormal embryonic/fetal subventricular zone morphology, abnormal neuronal precursor proliferation, absent inner cell mass proliferation, decreased brain size, decreased brain weight, decreased embryo size, embryonic growth retardation, [+]